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Targeted MS Analysis
l
ifi
di i
f d
i i i
d/
•
Ana yte‐spec c con t ons or ata acqu s t on an or
data analysis
•
Typically SIM or MS/MS (MRM) analysis
•
Known chromatographic behavior (retention times) and
MS data (MS or MS/MS spectra and ion ratios)
•
Screening of known adulterants
•
Quantitative analysis for compounds with reference
standards
Example:
‐
Lee et al., J. Pharm. Biomed. Anal. 83 (2013) 171– 178
(38 PDE5 i hibi
)
n tors