41 / 1544
Preoperative chemoRT or RT alone?
EORTC 22921
(1)
and FFCD 9203
(2)
: preoperative 5-FU
chemoRT superior over RT alone with respect to
pCR and LC, but no difference in:
Overall survival
Rate of sphincter sparing surgery
Occurrence of distant metastases
(1) Bosset et al., N Engl J Med 2006
(2) Gérard et al., J Clin Oncol 2006
4
Bosset et al, Lancet Oncol 2014