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What is the best measure of xerostomia?
•
Does the tolerance dose of parotid glands differ between
subjective measures, objective measures and patient reported
outcomes of xerostomia?
(data from the first multicenter randomized study of IMRT and
conventional RT)
•
Patient reported outcomes results are associated with a higher
tolerance dose (D50= 33 Gy)
•
LENT-SOMA subjective xerostomia is the most useful clinical
measure of salivary function (easily measured and strongly
associated with the dose-response of the parotid glands)
Miah
et al
, 2013