920 / 1544
LOGEUD
TD50
k
Rancati (2009)
46.0 + 1.8
9.95 + 3.46
0,00
0,10
0,20
0,30
0,40
0,50
0,60
0,70
0,80
0,90
1,00
20
30
40
50
60
70
80
Dose (Gy)
NTCP (LKB model)
all volume
2/3 volume
1/3 volume
LKB
TD50
m
n
Rancati (2009)
46.3 + 1.8
0.16 + 0.05 0.45 + 0.028
Laryngeal edema:
•Large volume effect
EUD<30-35 Gy (n=0.45)
• V50<27%;
mean dose <44 Gy
Rancati
et al
IJROBP 2009
Larynx is parallel for edema
(3/4)