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DYSPHAGIA

Organs: supraglottic larynx and constrictor muscles

Endpoints: aspiration and deglutition

Feng et al, 2006 (ASTRO):

evidence of a quantitatively

assessed

dose-volume effect

for disphagia & aspiration

(36 pts)

Aspiration

:

mean dose & V50-V65 to pharingeal

constrictors

, supraglottic larynx - correlated.

Most predictive: V65(PC)<50%