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Validation of QUANTEC guidelines for
xerostomia
•
Lee F
et al
, R&O, 2013
•
238 pts, EORTG QoL questionnaires
•
Validation of LKB parameters,
•
Beetz I
et al,
Acta Oncologica, 2014
•
307 pts, chemoradio, 3D CRT (56%), IMRT (44%)
•
Significanly
lower rates of xerostomia
in pts treated according
to
guidelines
, but the criteria do not completely protect aganist
xerostomia
•
Moiseenko
et al
, IJROBP 2012
•
66 pts,, flow measurements, gr 4 xerostomia; @3 mths, flow
decreases to <25% than pretreatment
•
Clinical use of the ”20 Gy spared-gland rule” is justified