919 / 1544
•
Larynx/edema gr 2
:
66 pts, videofluoroscopy assessed, fu=17.4m
mean dose or V%> 50 Gy
& neck stage (multivariate -
Sanguineti
et al
, IJROBP 2007)
V50<27%; mean dose < 43.5 Gy (EQD2)
•
Larynx/vocal disfunction
:
complex physiology
>66 Gy (prescription): decrease in function
but not 3D data (
Dornfeld
et al,
IJROBP 2007)
•
Risk factors
:
concurrent chemo to high dose RT
>double risk of laryngeal edema and
vocal dysfunction
Rancati
et al
, IJROBP, vol, 76, n3, S64-S69
LARYNX, edema
(2/4)