SPDS eBook March 2017

SMPR of Aloe Identification Key Points

Selectivity

Study

100% correct identification of

acetylated glucomannan

polysaccharides derived from

Aloe

vera

in the presence or absence of

potential adulterants listed in table

3.*

*100% correct analyses are expected. Some aberrations may be acceptable if the

aberrations are investigated, and acceptable explanations can be determined

and communicated to method users.

SMPR of Aloe Polysaccharide

Quantitation Key Points

•

Quantitation of water soluble Aloe vera

polysaccharides and the following organic acids

(acetic acid, lactic acid, malic acid and isocitric acid)

including the matrix(es) in which the polysaccharides

and the acids are found);

•

Any analytical technique that meets the method

performance requirements is acceptable;

•

It is expected that more than one technique will be

required;

•

May require developing aloe polysaccharide

standards for quantitation;