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Single Lab Validation of a Method for the Determination of β‐

Galactooligosaccharides in Infant Formula & Adult Nutritionals / Sean Austin (NRC, 

Lausanne)  

25 Jul 2016

CONFIDENTIAL

 ∙ This document may not be reproduced or disclosed to third parties without prior authorization 

Page 3 / 35

1

I N T R O D U C T I O N 

After opening a call for methods to determine β‐galactooligosaccharides (GOS) in infant formula and 

adult nutritionals, the AOAC received 2 method proposals.  Both were considered by the expert 

review panel (ERP), and both were rejected. One of the two previous methods was rejected due to a 

lack of specificity for GOS.  That method has since been modified to improve specificity and this 

report described the single lab validation (SLV) of that method.  

VALIDATION REPORT

FOR ERP USE ONLY

DO NOT DISTRIBUTE