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1761-Plat
12:00 pm
MISMATCH DEPENDENT TILT OF AMPHIPATHIC α-HELICAL ANTIMI-
CROBIAL PEPTIDES INSERTED IN POSITIVE SPONTANEOUS CURVATURE
LIPID MEMBRANES.
Erik Strandberg
, Jonathan Zerweck, Ariadna
Grau-Campistany, Marie-Claude Gagnon, Parvesh Wadhwani, Johannes
Reichert, Jochen Bürck, Jean-Francois Paquin, Michele Auger, Francesc
Rabanal, Anne S. Ulrich
1762-Plat
12:15 pm
TN-RAS, SYNAPTOTAGMIN1 C2AB, ANNEXINB12 AND AMPHIPHYSIN
NBAR CAN DISCRIMINATE SPHERICAL FROM CYLINDRICAL MEMBRANE
CURVATURE.
Artu’ Breuer
, Jannik Larsen, Kadla Røskva Rosholm, Søren L.
Pedersenb, Henrik K. Munch, Vadym Tkach, John J. Sakon, Thomas
Bjørnholm, Keith R. Weninger, Poul M. Bendix, Knud J. Jensen, Mark J.
Uline, Nikos S. Hatzakis, Dimitrios Stamou
1763-Plat
12:30 pm
BAR DOMAIN PROTEINS CAN DIFFER SUBSTANTIALLY IN THEIR CAPAC-
ITY TO GENERATE MEMBRANE CURVATURE.
Zhiming Chen
, Zheng Shi,
Katarzyna I. Jankowska, Tobias Baumgart
Platform
Intrinsically Disordered Proteins (IDP) and
Aggregates II
10:45 am - 12:45 pm, Room 515A
Co-Chairs
Edward Lemke, European Molecular Biology Laboratory, Germany
Sudipta Maiti, Tata Institute of Fundamental Research, India
1764-Plat
10:45 am
PLASTICITY OF NUCLEOPORIN NUCLEAR TRANSPORT RECEPTOR INTER-
ACTIONS - MOLECULAR DESCRIPTION OF A HIGHLY DYNAMIC, ULTRAFAST
INTERACTION MECHANISM.
Iker Valle Aramburu
, Davide Mercadante,
Sigrid Milles, Malene Ringkjøbing, Niccolò Banterle, Christine Koehler,
Swati Tyagi, Jane Clarke, Sarah L. Shammas, Martin Blackledge, Frauke
Gräter, Edward A. Lemke
1765-Plat
11:00 am
A HIDDEN STRUCTURAL TRANSITION ACCOMPANIES THE PROGRESSION
OF AMYLOID-ΒETA OLIGOMERS TO MATURE FIBRILS. Bappaditya
Chandra, Debanjan Bhowmik, Barun K. Maity, Debabrata Dhara, Kaustubh
Mote, Ravindra Venkatramani, Perunthiruthy K. Madhu,
Sudipta Maiti
1766-Plat
11:15 am
REGULATION OF MAMMALIAN DYNEIN INTERMEDIATE CHAIN.
Jing Jie
,
Elisar Barbar
1767-Plat
11:30 am
INTRINSICALLY DISORDERED PROTEINS: GATEKEEPERS OF THE NUCLEAR
PORE COMPLEX. Ali Ghavami, Liesbeth M. Veenhoff, Erik Van der
Giessen,
Patrick R. Onck
1768-Plat
11:45 am
CHARGE PATTERNED SEQUENCES FORM HELICAL STRUCTURES THROUGH
CHARGE NEUTRALIZATION.
Tyler S. Harmon
, Rohit V. Pappu
1769-Plat
12:00 pm
STRUCTURAL ENSEMBLES OF INTRINSICALLY DISORDERED PROTEINS
DEPEND STRONGLY ON FORCE FIELD: A COMPARISON TO EXPERIMENT.
Sarah Rauscher
, Vytautas Gapsys, Man Zhou, Qui Van, Michal Gajda,
Markus Zweckstetter, Joerg Enderlein, Bert L. de Groot, Helmut
Grubmüller
1770-Plat
12:15 pm
FACTORS MODULATING THE INTERACTION OF HUNTINGTIN WITH LIPID
MEMBRANES: IMPLICATIONS FOR HUNTINGTON’S DISEASE.
Justin
Legleiter
, James R. Arndt, Maxmore Chaibva, Xiang Gao, Pranav Jain,
Olivia Sarver, Stephen Valentine
1771-Plat
12:30 pm
ELECTROSTATIC CONTRIBUTIONS TO CALMODULIN INTERACTIONS WITH
CALCINEURIN.
Trevor P. Creamer
, Erik C. Cook
Platform
Calcium Signaling
10:45 am - 12:45 pm, Room 515B
Co-Chairs
Anne Carlson, University of Pittsburgh
Yubin Zhou, Texas A&M University
1772-Plat
10:45 am
CALCIUM SIGNALING REQUIRED FOR THE FAST POLYSPERMY BLOCK IN
XENOPUS LAEVIS. Katherine L. Wozniak,
Anne E. Carlson
1773-Plat
11:00 am
REGULATION OF THE CARDIAC L-TYPE CALCIUM CHANNEL BY THE CYCLIC
NUCLEOTIDE CROSS-TALK SIGNALING NETWORK.
Claire Y. Zhao
, Joseph
L. Greenstein, Raimond L. Winslow
1774-Plat
11:15 am
SR CONTRIBUTION TO CALCIUM CYCLING IN SINO-ATRIAL NODE CELLS:
AS SEEN FROM NANOSCALE ELECTRON MICROSCOPY AND NUMERICAL
MODELING.
V.Ramesh Iyer
, Oliver Monfredi, Victor Maltsev, Manuela
Lavorato, Michael Stern, Clara Franzini-Armstrong
1775-Plat
11:30 am
A C-TERMINAL SWITCH GATES THE ORAI1 CHANNEL.
Yandong Zhou
,
Xiangyu Cai, xianming wang, Natalia A. Loktionova, Xizhuo Wang, Robert
M. Nwokonko, Mohamed Trebak, Donald L. Gill
1776-Plat
11:45 am
HIGH-SPEED CONFOCAL IMAGING REVEALS COMPLEX CALCIUM TRAN-
SIENTS IN PLATELES.
János Vincze
, Renáta Hudák, János Kappelmayer,
László Csernoch
1777-Plat
12:00 pm
NEAR-INFRARED PHOTOACTIVATABLE CONTROL OF CALCIUM SIGNALING.
Lian He, Yuanwei Zhang, Guolin Ma, Peng Tan, Youjun Wang, Yun Huang,
Patrick Hogan, Gang Han,
Yubin Zhou
1778-Plat
12:15 pm
THE FUNCTION OF STROMAL INTERACTION MOLECULE 1 (STIM1) IN
HEART.
Guiling Zhao
, Hengtao Zhang, Tianyu Li, Didier X. P. Brochet, Paul
Rosenberg, W. Jonathan Lederer
1779-Plat
12:30 pm
COMPLEMENT-MEDIATED PURE CHEMOTAXIS OF HUMAN NEUTROPHILS
NEITHER REQUIRES NOR CAUSES BURSTS IN INTRACELLULAR CALCIUM
LEVELS.
Emmet A. Francis
, Volkmar Heinrich
Platform
Protein-Dynamics and Allostery I
10:45 am - 12:45 pm, Room 501ABC
Co-Chairs
Alessandro Cembran, University of Minnesota Duluth
Blake Mertz, West Virginia University
1780-Plat
10:45 am
DYNAMIC HETEROGENEITY AND THE ROLE OF NON-NATIVE CONTACTS
IN THE PROTEIN FOLDING/UNFOLDING TRANSITIONS.
Toshifumi Mori
,
Shinji Saito
1781-Plat
11:00 am
NIPAH VIRUS ENTRY INTO HOST CELL: INTER-MONOMER REARRANGE-
MENT SIGNALED BY RECEPTOR BINDING AT ALLOSTERIC SITE.
Priyanka
Dutta
, Sameer Varma