46 / 266
F
R
I
D
A
Y
S
U
N
D
A
Y
19
171-Symp
5:00 pm
MECHANISM AND FUNCTIONS OF PLATELET MECHANOSENSING.
Renhao Li
172-Symp
5:30 pm
CONFORMATIONAL PLASTICITY AND DRUGGABILITY OF MEMBRANE-
BOUND K-RAS.
Alemayehu A. Gorfe
Symposium
Structure and Motion of Cilia and Flagella
4:00 pm - 6:00 pm, Petree Hall D
Chair
Jonathan Howard, Yale University
173-Symp
4:00 pm
CRYO-ELECTRON TOMOGRAPHY PROVIDES A NEWWINDOW INTO CILI-
ARY STRUCTURE AND FUNCTION.
Daniela Nicastro
174-Symp
4:30 pm
STRUCTURAL GENETICS OF CILIA/FLAGELLA.
Masahide Kikkawa
175-Symp
5:00 pm
MOTOR COORDINATION UNDERLYING THE FLAGELLAR BEAT IN
CHLAMYDOMONAS.
Jonathon Howard
176-Symp
5:30 pm
SYNCHRONIZATION OF EUKARYOTIC FLAGELLA.
Raymond E. Goldstein
Symposium
DNA Nanostructures for Biophysics
4:00 pm - 6:00 pm, Room 502A
Chair
William Shih, Harvard University
177-Symp
4:00 pm
DNA NANOSTRUCTURES AS BUILDING BLOCKS FOR MOLECULAR
BIOPHYSICS AND FUTURE THERAPEUTICS.
William Shih
178-Symp
4:30 pm
CREATING PROGRAMMABLE DISORDER IN DNA ORIGAMI ARRAYS WITH
COMBINATORIAL PATTERNS.
Lulu Qian
, Grigory Tikhomirov, Philip
Petersen
179-Symp
5:00 pm
DNA ORIGAMI FOR NANOPORES: DESIGN, DEVELOPMENTS AND
CHALLENGES.
Ulrich F. Keyser
180-Symp
5:30 pm
NANOSCALE CONSTRUCTION AND IMAGING WITH DNA.
Peng Yin
Platform
Voltage-gated Channels (Na and Ca)
4:00 pm - 6:00 pm, Room 502B
Co-Chairs
Christopher Ahern, University of Iowa
Coeli Lopes, University of Rochester
181-Plat
4:00 pm
RATIONAL DESIGN AND SYNTHESIS OF A NOVEL MEMBRANE BINDING
NAV1.8 SELECTIVE INHIBITOR WITH IN VIVO ACTIVITY IN PAIN MODELS.
Christina I. Schroeder
, Jennifer Deuis, Sonia Troeria Henriques, Zoltan
Dekan, Marco Inserra, Mehdi Mobli, Irina Vetter
182-Plat
4:15 pm
SODIUM CHANNEL/LIGAND COMPLEX STRUCTURES AS A GUIDE FOR
RATIONAL DRUG DESIGN.
Altin Sula
, Paul DeCaen, Claire Naylor,
Geancarlo Zanatta, Claire Bagneris, David E. Clapham, David Pryde, B.A.
Wallace
183-Plat
4:30 pm
STRUCTURAL BASIS OF NAV1.7 INHIBITION BY AN ISOFORM-SELECTIVE
SMALL MOLECULE ANTAGONIST.
David H. Hackos
, Shivani Ahuja,
Susmith Mukund, Lunbin Deng, Kuldip Khakh, Elaine Chang, Clint Young,
Sophia Lin, J.P. Johnson Jr., Daniel F. Ortwine, Brian S. Safina, Daniel P.
Sutherlin, Charles J. Cohen, Christopher M. Koth, Jian Payandeh
184-Plat
4:45 pm
MUTATION-SPECIFIC CARDIAC RISK ASSESSMENT IN LQT3.
Elsa Ronzier
,
Alessandra Matavel, Yitschak Biton, Niels Otani, Wojciech Zareba, Arthur
J. Moss, Coeli Lopes
185-Plat
5:00 pm
GENETICALLY ENCODING SINGLE-MOLECULE FLUOROPHORES INTO ION
CHANNELS IN LIVING CELLS.
Lilia Leisle
, Rahul Chadda, Jason D. Galpin,
Janice L. Robertson, Christopher A. Ahern
186-Plat
5:15 pm
GABAPENTINOIDS SUPPRESS EARLY AFTERDEPOLARIZATIONS BY UNCOU-
PLING α
2
δ-1 SUBUNITS FROM CA
V
1.2 CHANNELS: IMPLICATIONS FOR CA
V
CHANNEL GATING-MODIFIERS AS A NEW CLASS OF ANTIARRHYTHMICS.
Nicoletta Savalli
, Marina Angelini, James N. Weiss, Riccardo Olcese
187-Plat
5:30 pm
BIOPHYSICAL CHARACTERIZATION OF THE HONEYBEE’S DSC1 ORTHOLOG
HIGHLIGHTS A NEW VOLTAGE DEPENDANT CALCIUM CHANNEL SUBFAM-
ILY.
Pascal Gosselin-Badaroudine
, Adrien Moreau, Louis Simard, Thierry
Cens, Matthieu Rousset, Pierre Charnet, Mohamed Chahine
188-Plat
5:45 pm
REGULATION OF MEMBRANE LOCALIZATION OF TYPE TWO VOLTAGE
GATED CALCIUM CHANNELS.
Mallory B. Scott
, Paul J. Kammermeier
Platform
Membrane Structure
4:00 pm - 6:00 pm, Room 515A
Co-Chairs
Lisa Della Ripa, University of Illinois at Urbana-Champaign
Tyler Reddy, University of Oxford, United Kingdom
189-Plat
4:00 pm
THE COMPLEX, ASYMMETRIC, ESCHERICHIA COLI ENVELOPE STUDIED BY
NEUTRON SCATTERING. Luke A. Clifton, Stephen A. Holt, Nico Paracini,
Arwel V. Hughes, Syma Khalid, Damien Jefferies,
Jeremy H. Lakey
190-Plat
4:15 pm
A COARSE GRAINED FORCE FIELD FOR PSEUDOMONAS AERUGINOSA
PAO1 LIPOPOLYSACCHARIDE.
Brad J. Van Oosten
, Thad A. Harroun
191-Plat
4:30 pm
MOLECULAR INSIGHTS INTO THE LOW PERMEABILITY BARRIER OF GRAM-
NEGATIVE PATHOGENS.
Cesar A. Lopez Bautista
, S. Gnanakaran, Helen
Zgurskaya
192-Plat
4:45 pm
COMPARTMENTAL VOLUME REGULATION OF E. COLI UNDER VARIOUS
GROWTH CONDITIONS.
Jonas van den Berg
, Bert Poolman
193-Plat
5:00 pm
ATOMIC RESOLUTION STUDIES OF STEROL INTERACTIONS BY SOLID-STATE
NMR SPECTROSCOPY.
Lisa A. Della Ripa
, Alexander G. Cioffi, Samantha
Phinney, Xiangyan Shi, Taras V. Pogorelov, Martin D. Burke, Chad M.
Rienstra
194-Plat
5:15 pm
INTERNATIONAL TRAVEL AWARDEE
STRUCTURAL CHARACTERIZATION ON ASYMMETRIC LIPID VESICLES AT
SUBNANOMETER RESOLUTION.
Barbara Geier
, DrewMarquardt,
Frederick Heberle, Milka Doktorova, John Katsaras, Georg Pabst