1385 / 1674
Group of second cancers at high dose sites:Esophagus, pleura, lung, bones &
connective tissues. Latency 5 years following BC diagnosis, by surgery type
Grantzau 2012
Berrington d Gonzalez, 2010
Grantzau 2012
Berrington d Gonzalez, 2010
Grantzau 2012
Berrington d Gonzalez, 2010
TOTAL; I
2
= 0%
TOTAL; I
2
= 0%
TOTAL; I
2
= 23%
1.45 (1.33-1.58)
86
1.54 (1.24-1.91)
14
1.46 (1.35-1.58) 100
1.28 (1.14-1.43)
84
1.35 (1.04-1.75)
16
1.29 (1.16-1.43) 100
1.50 (1.23-1.83)
41
1.74 (1.48-2.04)
59
1.64 (1.42-1.89) 100
Mastectomy & BCS
BCS
Mastectomy
Relative Risk (95% CI) IV Random
RR ES (95 CI%); Weight %
Surgery type
1
RT decreased risk
2
69,296 / 112,761
RT / Non-RT
12,104 / 14,494
50,278 / 112,761
4,416 / 5,632
RT
risk
19,018 / 112,761
3,041 / 5,632
4