Endpoint: Second Thyroid Cancer Overall RR
Overall number of studies:
Total number of Patients:
Second Thyroid cancers:
Treatment years:
Range of FU:
4
322,461
188
1961 to 2007
0.2 to 26 years
Relative Risk (95% CI) IV Random
RR ES (95 CI%); Weight %
Studies, number of pt.
RT
37%
NON-RT
63%
1.00 (0.66-1.51)
56
1.32 (0.49-3.57)
9
1.33 (0.39-4.53)
6
1.03 (0.58-1.82)
29
1.05 (0.78-1.43) 100
Huang 2001
Grantzau 2012
(61,442)
(46,176)
0.5
1
2
4
Roychounduri 2004
Kirova 2007
(16,705)
(194,798)
TOTAL; I
2
= 0%
RT decreased risk
RT
increased
risk