1379 / 1674
Endpoint: Second Esophagus Cancer by time since BC diagnosis
Relative Risk (95% CI) IV Random
1.19 (0.60-2.35)
26
2.21 (1.42-3.45)
42
0.91 (0.37-2.25)
17
1.46 (0.57-3.76)
16
1.53 (1.01-2.31) 100
1.81 (1.03-3.19)
55
0.64 (0.17-2.39)
10
1.89 (0.57-6.30)
12
1.56 (1.03-2.38) 100
1.48 (0.62-3.53)
23
2.19 (1.07-4.49) 87
2.07 (0.32-13.39) 13
2.17 (1.11-4.25) 100
1
0.5
2
4
RR ES (95 CI%); Weight %
Latency ≥ 5 years
Latency ≥ 10 years
Latency ≥ 15 years
Roychounduri 2004
Zablotska 2005, Mastectomy
Zablotska 2005, BCS
Grantzau 2012
TOTAL; I
2
= 30%
Roychounduri 2004
Zablotska 2005, Mastectomy
Zablotska 2005, BCS
Grantzau 2012
TOTAL; I
2
= 0%
TOTAL; I
2
= 0%
Grantzau 2012
Roychounduri 2004
Latency period
RT decreased risk
RT
increased
risk