Endpoint: Second Thyroid cancer
by time since BC diagnosis
Huang 2001
Huang 2001
Roychounduri 2004
Roychounduri 2004
Grantzau 2012
Grantzau 2012
TOTAL; I
2
= 0%
TOTAL; I
2
= 0%
Latency ≥ 5 years
Latency ≥ 15 years
Relative Risk (95% CI) IV Random
RR ES (95 CI%); Weight %
Latency period
0.81 (0.44-1.50)
63
0.96 (0.59-1.57) 100
1.49 (0.48-4.63)
18
1.11 (0.36-3.43)
19
2.56 (0.32-20.50)
35
1.70 (0.18-16.04)
30
2.21 (0.64-7.61) 100
2.39 (0.29-19.82)
34
0.5 1 2 4
RT decreased risk
RT
increased
risk
Huang 2001
Roychounduri 2004
Grantzau 2012
TOTAL; I
2
= 0%
Latency ≥ 10 years
1.25 (0.19-18.34)
17
1.53 (0.69-3.39) 100
1.37 (0.50-3.75)
62
2.57 (0.45-14.74)
21