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Endpoint: Second Thyroid cancer

by time since BC diagnosis

Huang 2001

Huang 2001

Roychounduri 2004

Roychounduri 2004

Grantzau 2012

Grantzau 2012

TOTAL; I

2

= 0%

TOTAL; I

2

= 0%

Latency ≥ 5 years

Latency ≥ 15 years

Relative Risk (95% CI) IV Random

RR ES (95 CI%); Weight %

Latency period

0.81 (0.44-1.50)

63

0.96 (0.59-1.57) 100

1.49 (0.48-4.63)

18

1.11 (0.36-3.43)

19

2.56 (0.32-20.50)

35

1.70 (0.18-16.04)

30

2.21 (0.64-7.61) 100

2.39 (0.29-19.82)

34

0.5 1 2 4

RT decreased risk

RT

increased

risk

Huang 2001

Roychounduri 2004

Grantzau 2012

TOTAL; I

2

= 0%

Latency ≥ 10 years

1.25 (0.19-18.34)

17

1.53 (0.69-3.39) 100

1.37 (0.50-3.75)

62

2.57 (0.45-14.74)

21