Grid-based Method
Random-Sampling Method
Voxel-size
Dose value
dV = V/N
N = sampling points
ct local density
ROI/VOI
Inverse Optimization and Planning
(2000 – today)
Attention:
The dose distribution is analysed on the basis of a finite number of dose points, the
sampling points. The sampling method can be:
•
regular
3D grid (dose grid) or
•
random
(quasi) sampling or
•
geometry/implant
adapted




