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Grid-based Method

Random-Sampling Method

Voxel-size

Dose value

dV = V/N

N = sampling points

ct local density

ROI/VOI

Inverse Optimization and Planning

(2000 – today)

Attention:

The dose distribution is analysed on the basis of a finite number of dose points, the

sampling points. The sampling method can be:

regular

3D grid (dose grid) or

random

(quasi) sampling or

geometry/implant

adapted