( )
(
)
( )
[
]
[
]
1
1
∑
=
−
− Θ =
i
N
j
p
i
j
i
L
i
j
i
L
i
i
d D d D
N
f
x
x
Low-Objective for PTV
D
L
= D
V
for V
100%
L
H
( )
(
)
( )
[
]
[
]
1
1
∑
=
−
− Θ =
i
N
j
p i
H
i
j
i
H
i
j
i
i
D d D d
N
f
x
x
High-Objective for PTV
D
H
= D
V
for V
0%
L
H
General Form of an
Objective Function
and DVH
Inverse Optimisation and Planning
(2000 – today)




