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Second tumor:

Lung cancer

Increased lung cancer risk

in breast cancer patients is largely attributed to RT

Association between RT and subsequent lung cancer was found stronger for the

ipsilateral

lung

Postmastectomy

RT (often including supraclavicular, axillary, or internal

mammary nodal region):

2 to 3-fold increased risk

after 10+ years

RT after

breast conserving surgery

(less often including regional lymph node

irradiation): impact RT is

less certain

21

Clinical data: breast cancer

2

nd

tumors in patients treated for BREAST CANCER