Second tumor:
Lung cancer
Increased lung cancer risk
in breast cancer patients is largely attributed to RT
Association between RT and subsequent lung cancer was found stronger for the
ipsilateral
lung
Postmastectomy
RT (often including supraclavicular, axillary, or internal
mammary nodal region):
2 to 3-fold increased risk
after 10+ years
RT after
breast conserving surgery
(less often including regional lymph node
irradiation): impact RT is
less certain
21
Clinical data: breast cancer
2
nd
tumors in patients treated for BREAST CANCER