Second tumor:
Soft tissue sarcoma
15y incidence
of soft tissue sarcoma after RT
<0.5%
,
but
ERR=600%
relative to
general population
Rubino et al, 2005
: all soft tissue and bone sarcomas in irradiated women, were
located in irradiated fields or upper ipsilateral arm (
high dose areas
)
22
Clinical data: breast cancer
2
nd
tumors in patients treated for BREAST CANCER