1448-1449 / 2605
Chung CS, Yock TI, Nelson K, Xu Y, Keating NL, Tarbell NJ.
Incidence of second malignancies among patients treated with proton
versus photon radiation.
Int J Radiat Oncol Biol Phys. 2013 87:46-52
Retrospective cohort study of
558 patients
treated with proton radiation
from 1973 to 2001 at the Harvard Cyclotron in Cambridge, MA and 558
matched patients treated with photon therapy. Patients were matched
by age at radiation treatment, sex, year of treatment, cancer histology,
and site.
RESULTS:
Median duration of follow-up was
6.7 years
.
Second malignancies occurred in 29
proton
patients (
5.2%
) and
42
photon
patients (
7.5%
).
Proton therapy is not associated with an increased
risk of second malignancy !!!
Carbon Ions ????