There is increasing concern about
radiotherapy-related second cancers
As younger patients are treated, with longer life expectancy,
RT-induced second malignancies
will likely assume increasing importance
➢
Compared to the older 3-D conformal radiotherapy, modern
IMRT techniques
minimize
the amount of normal tissue getting
high doses
➢
But IMRT does result in
larger volumes
of normal tissue
getting
lower doses
(
more fields and more leakage
)
●
Which is preferable in terms of second cancers ?
➢
Small volumes of normal tissue getting high doses
(3D-CRT)
➢
Larger volumes of normal tissue getting low doses
(IMRT)