1432-1433 / 2605
Single cell
microbeam
Nearby cells sustain genomic damage in the
form of gene mutations and chromosomal
alterations even though they have not
received a direct dose of radiation
Radiation-induced bystander effects
„
Non targeted“ effects of ionizing radiation
Intercellular
communication via gap-
junctions:
ROS, NO
Cytokines
(TNF α, interleukin 1, 8, TGF ß)