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Radiation induced cancers
•
Spectrum
of Ca is same as that occurring naturally
•
Severity
of induced Ca is independent of dose
•
Probability
of Ca-induction increases with dose with no
threshold.
•
This is known as
stochastic
effect
•
Mechanism
is that cancer can arise from a single
mutation in a single cell
Cancer is a mul--step induc-on over 10 - 20 yrs