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Double Strand Break (DBS)
limited degradation from
5‘ ends
pairing of one end with
maternal chromosome
(template)
DNA synthesis, joint
molecule
Christmann et al. Toxicology 193 (2003)
DNA repair:
homologeous endjoining (HEJ)
Slow but high fidelity
repair f DNA by
recovering genetic
information from the
homologeous
chromosome