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Why do mammalian genomes

tolerate error-prone repair ?

because > 98% of the DNA sequence is non-coding !

Satellite DNA in the region of

centromers

and

telomers

Coding

genes

separated by

repetitive DNA elements

(~ 1.5%)

(SINE

and

LINE):

Short and long

interspersed repetitive elements,

consisting of

introns

and

regulatory sequences

(~ 24%)

,

repetitive DNA

(~ 59%)

and

non-

coding DNA

(~ 15%)