Why do mammalian genomes
tolerate error-prone repair ?
because > 98% of the DNA sequence is non-coding !
Satellite DNA in the region of
centromers
and
telomers
Coding
genes
separated by
repetitive DNA elements
(~ 1.5%)
(SINE
and
LINE):
Short and long
interspersed repetitive elements,
consisting of
introns
and
regulatory sequences
(~ 24%)
,
repetitive DNA
(~ 59%)
and
non-
coding DNA
(~ 15%)