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Normal tissue effects

Hypofractionation with its enormous increases in dose

may be

feasible, if the organ is a good approximation to a “

parallel

organ

” so that the loss of such small

volume

of functioning

tissue is tolerated, and if it contains no particularly sensitive

structures or organs of risk.

Serial organ

Parallel organ

Spinal cord, GI tract, etc

×

Lung, Liver, Bone, etc

×