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The response to radiation of tumors and
normal proliferative tissues (responsible for
acute reactions) substantially differs from
that of normal late-responding tissues
Normal tissue effects
Response to radiation
Tumors and normal proliferative tssues
:
cell injury mechanism is largely regulated by
coefficient α (lethal single-impact injury)
Late responding normal tissues:
coefficient β (lethal injury due to accumulation of
sub-lethal injury) predominates