IMRT Course 2016

1702-1703 / 2953

NTCP model structure
Regression models cannot handle 3D dose distributions or DVHs; requires a
summary measure φ, e.g. mean dose, which takes the volume effect into
account.
The most widely used (Lyman) model uses a cumulative normal function with 2
parameters: φ50 and m. Additional parameters might be needed for the DVH
summary.
05/04/2016