Dose-volume constraints
•
The relevant dose-volume parameter depends on the volume effect
•
Small volume effect: maximum dose
•
Large volume effet:
V
x
or mean dose
•
Emami et al. (IJROBP 1991) published tolerance values for partial organ
irradiation
•
The QUANTEC initiative (IJROBP 2010) is a special issue with one article
per organ
05/04/2016