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106

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

Tuesday, February 10

7:30

am

–5:00

pm

, C

harles

S

treet

L

obby

Registration/Information

8:00

am

–9:00

am

, R

oom

327/328/329

Biophysical Society Business Meeting

8:00

am

–4:30

pm

, H

all

C

Poster Viewing

8:00

am

–5:30

pm

, R

oom

301/302/303

Career Center

8:15

am

–10:15

am

, B

allroom

I

Symposium

Biophysics of RNA Processing: Degradation,

Splicing, DEAD Box Proteins

Chair

Sun Hur, Harvard University

1684-S

ymp

8:15

am

INSIGHTS INTO HELICASE EVOLUTION FROM THE

SPECIFICITY AND MECHANISM OF A DEAD-BOX PROTEIN.

Anna L. Mallam

, David J. Sidote, Alan M. Lambowitz

1685-S

ymp

8:45

am

SINGLE-MOLECULE IMAGING OF PRE-MRNA SPLICING.

Sanjay Tyagi

1686-S

ymp

9:15

am

AUXILIARY FACTORS AND RNA SUBSTRATES REGULATE

DEAD-BOX PROTEIN ACTIVITY BY MODULATION OF THE

DEAD-BOX PROTEIN CONFORMATIONAL CYCLE. Ulf Harms,

Alexandra Z. Andreou, Airat Gubaev,

Dagmar Klostermeier

1687-S

ymp

9:45

am

MOLECULAR MECHANISMS OF VIRAL RNA DETECTION:

RIG-I AND MDA5.

Sun Hur

8:15

am

–10:15

am

, B

allroom

II

Symposium

Molecules of Memory: Glutamate Receptor

Channels

Chair

Mark Mayer, NIH

1688-S

ymp

8:15

am

CONFORMATIONAL CHANGES UNDERLYING GLUTAMATE

RECEPTOR GATING.

Mark Mayer

1689-S

ymp

8:45

am

AMPA RECEPTOR STRUCTURE, FUNCTION, AND DYNAMICS.

Robert E. Oswald

, Ahmed H. Ahmed, Christopher P. Ptak, Madeline

Martinez

1690-S

ymp

9:15

am

INTRACELLULAR DOMAINS OF NMDA RECEPTORS

CONTROL CHANNEL PERMEATION AND GATING

PROPERTIES.

Gabriela K. Popescu

1691-S

ymp

9:45

am

NMDA RECEPTORS AS DYNAMIC ALLOSTERIC MACHINES.

Pierre Paoletti

8:15

am

–10:15

am

, B

allroom

III

Platform

Single-Molecule Spectroscopy

Co-Chairs

H. Peter Lu, Bowling Green State University

Lori Goldner, University of Massachusetts

1692-P

lat

8:15

am

NMDA RECEPTOR ION CHANNEL DYNAMICS IN

LIVING CELLS BY A NOVEL SINGLE-MOLECULE PATCH-

CLAMP FRET MICROSCOPY: REVEALING THE MULTIPLE

CONFORMATIONAL STATES ASSOCIATED WITH A CHANNEL

AT ITS ELECTRICAL OFF STATE. Dibyendu Sasmal,

H. Peter Lu

1693-P

lat

8:30

am

EXPLORING TAU CONFORMATIONS AT THE SINGLE-

MOLECULE LEVEL IN A MICROFLUIDIC TRAP.

Randall H. Goldsmith

, Sharla Wood, Lydia Manger, Michael Holden,

Martin Margittai

1694-P

lat

8:45

am

3D TRACKING OF SINGLE QUANTUM DOTS THROUGH

OFF-FOCUS IMAGING.

Lucia Gardini

, Marco Capitanio, Francesco

Saverio Pavone

1695-P

lat

9:00

am

DECONSTRUCTING PIFE: A SPECTROSCOPIC

INVESTIGATION OF THE “PROTEIN INDUCED

FLUORESCENCE ENHANCEMENT” PHENOMENON IN CY3.

Elana Maria Shepherd Stennett, Monika Anna Ciuba,

Marcia Levitus

1696-P

lat

9:15

am

FABRICATION AND SURFACE FUNCTIONALIZATION OF

HIGHLY BIREFRINGENT RUTILE PARTICLES FOR TRAPPING

IN AN OPTICAL TORQUE WRENCH.

Seungkyu Ha

, Yera

Ussembayev, Richard Janissen, Maarten van Oene, Nynke H. Dekker

1697-P

lat

9:30

am

ELECTRON PARAMAGNETIC RESONANCE FROM A SINGLE

BIOMOLECULE.

Richelle M. Teeling-Smith

, Young Woo Jung,

Nicolas J. Scozzaro, Jeremy Cardellino, Isaac Rampersaud, Justin A.

North, Marek Simon, Vidya P. Bhallamudi, Arfaan Rampersaud, Ezekiel

Johnston-Halperin, Michael G. Poirier, P. Chris Hammel

1698-P

lat

9:45

am

DYNAMICS OF POLYMERIC PROTEIN ASSEMBLIES IN LIVE

CELLS REVEALED BY FLUORESCENCE POLARIZATION

IMAGING OF SINGLE MOLECULES.

Shalin B. Mehta

, Molly

McQuilken, Patricia Occhipinti, Amitabh Verma, Rudolf Oldenbourg,

Amy S. Gladfelter, Tomomi Tani

1699-P

lat

10:00

am

SINGLE-MOLECULE-SENSITIVE FRET IN FREELY-DIFFUSING

ATTOLITER DROPLETS. Peker Milas, Sheema Rahmanseresht, Kieran

P. Ramos, Ben D. Gamari,

Lori S. Goldner