Biophysical Society 59th Annual Meeting Program Guide

112 / 294

112 Biophysical Society 59th Annual Meeting, Baltimore, Maryland
1784-Plat 11:45 am
ELECTROMAGNETIC TWEEZERS WITH INDEPENDENT
FORCE AND TORQUE CONTROL. Chang Jiang , Troy A.
Lionberger, Diane M. Wiener, Edgar Meyhöfer
1785-Plat 12:00 pm
SURFACE-FREE SINGLE-MOLECULE FORCE SPECTROSCOPY.
Yan Jiang, Wesley Wong
1786-Plat 12:15 pm
HIGH-SPEED FORCE SPECTROSCOPY UNBINDS
STREPTAVIDIN-BIOTIN AT THE VELOCITY OF MOLECULAR
DYNAMICS SIMULATIONS. Felix Rico, Andreas Russek, Helmut
Grubmueller, Simon Scheuring
1787-Plat 12:30 pm
THE PRINCESS AND THE PEA: A STORY OF CELL MECHANICS.
Mehdi Roeinpeikar, Qian Xu, Xuefeng Wang, Taekjip Ha
10:45 am–12:45 pm , Room 316/317
Platform
Protein-Small Molecule Interactions
Co-Chairs
Jürgen Bosch, Johns Hopkins University
Sonya Hanson, Memorial Sloan Kettering Cancer Center
1788-Plat 10:45 am
BIASING POTENTIAL REPLICA EXCHANGE MULTI-SITE
λ-DYNAMICS FOR EFFICIENT FREE ENERGY CALCULATIONS
OF PROTEIN-LIGAND INTERACTIONS. Kira A. Armacost, Garrett
B. Goh, Charles L. Brooks
1789-Plat 11:00 am
SURVEY OF PHOSPHORYLATION NEAR DRUG BINDING SITES
IN THE PROTEIN DATA BANK (PDB) AND THEIR EFFECTS.
Kyle P. Smith, Kathleen M. Gifford, Joshua S. Waitzman, Sarah E. Rice
1790-Plat 11:15 am education travel awardee
IDENTIFICATION AND CHARACTERIZATION OF PROTEIN-
PROTEIN INTERACTION EFFECTORS TARGETING THE
INVASION MACHINERY OF THE MALARIA PARASITE.
Lauren E. Boucher, Christine S. Hopp, Photini Sinnis, Jürgen Bosch
1791-Plat 11:30 am
ABSOLUTE BINDING FREE ENERGY CALCULATIONS OF
BROMODOMAIN INHIBITORS. Matteo Aldeghi , Stefan Knapp,
Alexander Heifetz, John J. Barker, Michael J. Bodkin, Richard J. Law,
Philip C. Biggin
1792-Plat 11:45 am
POSITIVE MODULATORS OF GLYCINE RECEPTORS
WITH ANALGESIC POTENTIAL IDENTIFIED BY VIRTUAL
SCREENING. Marta M. Wells , David D. Mowrey, Edom Seyoum,
Tianmo Sun, Yan Xu, Pei Tang
1793-Plat 12:00 pm
GREEN AND BLACK TEA POLYPHENOLS MECHANISTICALLY
INHIBIT THE AGGREGATION OF AMYLOID-β IN ALZHEIMER’S
DISEASE. Shelby E. Chastain, Melissa Moss
1794-Plat 12:15 pm
EFFECT OF REACTIVE ALDEHYDES ON IONOPHORE-
MEDIATED TRANSMEMBRANE TRANSLOCATIONS OF H+ AND
K+ . Alina A. Pashkovskaya, Elena E. Pohl
1795-Plat 12:30 pm
DEVELOPING HIGH-THROUGHPUT FLUORESCENCE-BASED
ASSAYS FOR MEASURING KINASE INHIBITOR FREE ENERGIES
OF BINDING. Sonya M. Hanson, Jan-Hendrik Prinz, Julie M. Behr,
Patrick B. Grinaway, Arien S. Rustenburg, Kyle A. Beauchamp, Daniel L.
Parton, John D. Chodera
12:00 pm–1:30 pm, Room 331/332
Funding Opportunities for Faculty at
Primarily Undergraduate Institutions
The Education Committee is hosting this session aimed at helping PUI
faculty find funding sources that will help them to establish or maintain
an active and productive undergraduate research laboratory.
Speakers
Jean Chin, NIGMS
Kamal Shukla, NSF
12:00 pm–2:00 pm, Room 318/319
Postdoc to Faculty Q&A:
Transitions Forum and Luncheon
This question-and-answer luncheon, sponsored by the Committee for
Professional Opportunities for Women (CPOW), is designed for postdocs
finishing and actively applying for academic faculty positions. New
faculty and recently tenured faculty in basic science and/or medical school
departments will lead the discussion, as well as experienced senior-level
faculty who have served as department chairs and/or part of faculty search
committees. Topics for discussion include how to prepare the curriculum
vitae, the interview process, networking, how to negotiate the job offer,
and advice for new faculty as they balance research with their department
obligations. Pre-registration was required for lunch. If you are interested in
attending and did not register in advance, you are welcome to participate
in the discussion on a space-available basis.
Speakers
Sarah Bondos, Texas A&M Health Science Center
Jane Clarke, University of Cambridge, United Kingdom
Barry Grant, University of Michigan
Anne Hinderliter, University of Minnesota, Duluth
Rohit Pappu, Washington University, St. Louis
Catherine Royer, Rensselaer Polytechnic Institute
Madeline Shea, University of Iowa Carver College of Medicine
Shai Silberberg, NIH/NINDS
Joanna Sulkowska, University of Warsaw, Poland
12:30 pm–2:00 pm, Hall C, Room B
Exhibitor Presentation
Nanion Technologies GmbH
Measure More Membrane: Cells, Bilayers and Transporter Activity
The Port-a-Patch turned 10 years old last year, and is going stronger than
ever. It’s still the smallest patch clamp rig in the world, and makes patch
clamp recordings accessible to anyone spending a couple of hours with
it. Giga-seal recordings and the excellent voltage-clamp of the cellular
membrane ensure high quality data, and the Port-a-Patch add-ons allow
unprecedented experimental freedom, including temperature control,
internal perfusion, automated action potential recordings, and recordings
from primary and stem cell-derived cells.
The Orbit 16 is a parallel device for efficient formation of and recordings
from up to 16 artificial bilayers at once, for parallel bilayer-reconstitution
of ion channels and nanopores. Using Micro Electrode Cavity Array
(MECA, Ionera), a 4 x 4 array of circular micro-cavities in a highly inert
polymer, the bilayer is automatically formed by remotely actuated painting
(Ionera- SPREAD), which all will be demonstrated during the session.