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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
T
U
E
S
D
A
Y
1817-P
lat
5:15
pm
MYOSIN-BINDING PROTEIN C CORRECTS AN INTRINSIC
NON-UNIFORMITY IN CARDIAC EXCITATION-
CONTRACTION COUPLING.
Michael J. Previs
, Benjamin L.
Prosser, Ji Young Mun, Samantha Beck Previs, James Gulick, Kyounghwan
Lee, Jeffrey Robbins, Roger Craig, W. Jonathan Lederer, David M.
Warshaw
1818-P
lat
5:30
pm
DIRECT DETECTION OF THE THERMODYNAMICS AND
STRUCTURAL KINETICS OF A 2-COLOR SERCA BIOSENSOR BY
TRANSIENT TIME-RESOLVED FRET. Simon J. Gruber,
Rebecca Goldblum
, Jenica Zhong, Kurt Peterson, Tory M. Schaaf, Joseph
M. Autry, Gregory D. Gillispie, David D. Thomas, Joseph M. Muretta
1819-P
lat
5:45
pm
PHOSPHOLAMBAN-INDEPENDENT ADRENERGIC RESERVE IN
SERCA2 ABLATED HEARTS.
Frazer I. Heinis
, Joseph M. Metzger
4:00
pm
–6:00
pm
, R
oom
307/308
Platform
Protein Dynamics and Allostery II
Co-Chairs
James Munro, Tufts University
Joana Paulino, Florida State University
1820-P
lat
4:00
pm
CONFORMATIONAL DYNAMICS OF SINGLE HIV-1 ENVELOPE
PROTEINS ON THE SURFACE OF NATIVE VIRIONS.
James B. Munro
, Jason Gorman, Xiaochu Ma, Zhou Zhou, James
Arthos, Dennis Burton, Wayne Koff, Joel Courter, Amos Smith, Peter
Kwong, Scott Blanchard, Walther Mothes
1821-P
lat
4:15
pm
ALLOSTERIC REGULATION OF NIPAH VIRUS ENTRY INTO
HOST CELLS.
Sameer Varma
, Priyanka Dutta, Mohsen Botlani
1822-P
lat
4:30
pm
SPECIFIC PROTEIN-LIPID INTERACTIONS STABILIZE AN
ACTIVE STATE OF THE BETA 2 ADRENERGIC RECEPTOR.
Chris Neale
, Henry D. Herce, Régis Pomès, Angel E. García
1823-P
lat
4:45
pm
DYNAMICS OF M2 PROTON CHANNEL: INSIGHTS INTO THE
MOTIONS OF THE PRIMARY AND SECONDARY GATES.
Joana Paulino
, Ivan Hung, Timothy A. Cross
1824-P
lat
5:00
pm
IDENTIFICATION OF AN ENDOGENOUS ALLOSTERIC
MODULATOR’S BINDING SITE AT THE HUMAN
CANNABINOID-1 RECEPTOR, USING FORCED-BIASED
METROPOLIS MONTE CARLO SIMULATED ANNEALING
METHOD (MMC) AND MOLECULAR DYNAMICS.
Derek M. Shore
, Dow P. Hurst, Diane L. Lynch, Patricia H. Reggio
1825-P
lat
5:15
pm
LIGAND-G PROTEIN ALLOSTERIC COMMUNICATION
THROUGH INTERNAL WATERS IN GPCR COMPLEXES.
Roman Osman
, Jose Carlos Gomez, Mihaly Mezei, Dov Barak, Arnau
Cordomi, Leonardo Pardo
1826-P
lat
5:30
pm
INSERTION OF
β
-BARREL PROTEINS IN GRAM-NEGATIVE
BACTERIA.
Karl Lundquist
, James C. Gumbart
1827-P
lat
5:45
pm
SUPER-RESOLUTION MAPPING OF THE DYNAMICS OF
PERIODIC STRUCTURAL DEFECTS IN COLLAGEN FIBRILS.
Andrew Dittmore
, Jonathan Silver, Barry Marmer, Gregory I. Goldberg,
Keir C. Neuman
4:00
pm
–6:00
pm
, R
oom
309/310
Platform
Systems Biophysics
Co-Chairs
Cees Decker, Delft University of Technology, The Netherlands
Hye Ran Koh, University of Illinois at Urbana-Champaign
1828-P
lat
4:00
pm
SYMMETRY AND SCALE ORIENT MIN OSCILLATION
PATTERNS IN BACTERIAL SHAPE SCULPTURES. Fabai Wu, bas
van Schie, Juan Keymer,
Cees Dekker
1829-P
lat
4:15
pm
QUANTITATIVE ANALYSIS OF RNA INTERFERENCE BY MRNA
COUTING AT SINGLE-CELL LEVEL.
Hye Ran Koh
, Sua Myong
1830-P
lat
4:30
pm
ENVIRONMENTAL STATISTICS AND OPTIMAL REGULATION.
David A. Sivak
, Matt Thomson
1831-P
lat
4:45
pm
FUNDAMENTAL CONSTRAINTS ON THE ABUNDANCES OF
CHEMOTAXIS PROTEINS.
Anne-Florence Bitbol
, Ned S. Wingreen
1832-P
lat
5:00
pm
EARLY LINEAGE BIFURCATION DURING DIFFERENTIATION
OF EMBRYONIC STEM CELLS REVEALED BY SINGLE-CELL
TRANSCRIPTOMICS.
Stefan Semrau
, Johanna Goldmann,
Magali Soumillon, Tarjei Mikkelsen, Rudolf Jaenisch, Alexander van
Oudenaarden
1833-P
lat
5:15
pm
EMERGENT BEHAVIOURS OF STEM CELLS IN
ORGANOGENESIS DEMONSTRATED BY HYBRID MODELLING.
Benjamin A. Hall
, Nir Piterman, Alex Hajnal, Jasmin Fisher
1834-P
lat
5:30
pm
PHAGE DNA DYNAMICS IN CORRELATION WITH CELL FATES.
Qiuyan Shao, Alexander Hawkins,
Lanying Zeng
1835-P
lat
5:45
pm
SYSTEMS MECHANO-BIOLOGY: TENSION-INHIBITED
PROTEIN TURNOVER IS SUFFICIENT TO PHYSICALLY
CONTROL GENE CIRCUITS.
P. C. Dave P. Dingal
, Dennis E.
Discher
4:00
pm
–6:00
pm
, R
oom
314/315
Platform
Ion Channel Regulatory Mechanisms
Co-Chairs
Takanari Inove, Johns Hopkins University
Michelle Yen, Stanford University
1836-P
lat
4:00
pm
COUPLING OF DISTINCT ION CHANNEL TYPES IN NEURONS
MEDIATED BY AKAP79/150. Jie Zhang,
Mark S. Shapiro