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114

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

1797-S

ymp

4:30

pm

IN VIVO-STUDIES OF GPCR CONFORMATIONAL CHANGES

USING FLUORESCENCE-BASED ASSAYS.

Martin Lohse

1798-S

ymp

5:00

pm

LIPID ORGANIZATION OF THE PLASMA MEMBRANE. Helgi I.

Ingolfsson, Peter Tieleman,

Siewert Marrink

1799-S

ymp

5:30

pm

DIFFERENTIAL PHOSPHATIDYLSERINE RECOGNITION BY

THE TIM FAMILY OF IMMUNE REGULATORY RECEPTORS.

Ka Yee C. Lee

4:00

pm

–6:00

pm

, B

allroom

II

Symposium

Extremophiles: Testing the Physical Limits of

Living Systems

Chair

Catherine Royer, Rensselaer Polytechnic Institute

1800-S

ymp

4:00

pm

PROTEIN FOLDING AT EXTREME TEMPERATURES: CURRENT

ISSUES.

Georges Feller

1801-S

ymp

4:30

pm

USING SINGLE MOLECULE FORCE SPECTROSCOPY TO PROBE

PROTEINS FROM EXTREMOPHILES.

Lorna Dougan

1802-S

ymp

5:00

pm

MECHANISMS OF PRESSURE EFFECTS IN BIOLOGY: FROM

PROTEINS TO LIVE BACTERIA.

Catherine Ann Royer

1803-S

ymp

5:30

pm

WHAT LIMITS MICROBIAL GROWTH AT HIGH PRESSURE?

Doug Bartlett

4:00

pm

–6:00

pm

, B

allroom

III

Platform

Optical Microscopy and Super-Resolution

Imaging II

Co-Chairs

Luca Lanzano, Italian Institute of Technology, Italy

Johan Elf, Uppsala University, Sweden

1804-P

lat

4:00

pm

BACKGROUND-FREE SUPER-RESOLUTION MICROSCOPY

OF SUBCELLULAR STRUCTURES BY LIFETIME TUNING AND

PHOTONS SEPARATION.

Luca Lanzano

, Ivan Coto Hernandez,

Marco Castello, Enrico Gratton, Alberto Diaspro, Giuseppe Vicidomini

1805-P

lat

4:15

pm

INVESTIGATING CELLULAR FOCAL ADHESIONS ON NANO-

PATTERNED SUBSTRATES WITH DUAL COLOR PHOTO-

ACTIVATED LOCALIZATION MICROSCOPY.

Hendrik G. Deschout

, Michelle A. Baird, Michael W. Davidson, Joachim

P. Spatz, Aleksandra Radenovic

1806-P

lat

4:30

pm

minority affairs

travel awardee

QUANTITATIVE ANALYSIS OF NANOSCALE LIPID BILAYER

MODIFICATIONS VIA SECOND HARMONIC GENERATING

PROBES.

Erick K. Moen

, Hope Beier, Andrea Armani, Bennett Ibey

1807-P

lat

4:45

pm

FUNCTIONAL IMAGING OF INTACT PANCREATIC ISLETS BY

INVERTED SELECTIVE PLANE ILLUMINATION MICROSCOPY.

Zeno Lavagnino

, David W. Piston

1808-P

lat

5:00

pm

SINGLE MOLECULE TRACKING IN LIVING CELLS -

MULTISTEP REACTIONS, SIMULATED MICROSCOPY AND

NEW ANALYSIS METHODS. Martin Lindén,

Johan Elf

1809-P

lat

5:15

pm

MAPPING THE DIFFUSIVE ROUTE OF NANOPARTICLES

IN LIVE CELLS REVEALS SHAPE TO CONTROL NUCLEAR

ACCESSIBILITY.

Elizabeth Hinde

, Hien T. Duong, Bunyamin

Karagoz, Justin J. Gooding, Cyrille Boyer, Katharina Gaus

1810-P

lat

5:30

pm

CORRELATIVE IPALM AND PLATINUM REPLICA ELECTRON

TOMOGRAPHY PINPOINTS ENDOCYTIC PROTEINS ON THE

MAMMALIAN CELL CORTEX IN 3D.

Kem A. Sochacki

, Gleb

Shtengel, Harald F. Hess, Justin W. Taraska

1811-P

lat

5:45

pm

REFSOFI FOR IMAGING PROTEIN-PROTEIN INTERACTIONS

IN LIVING CELLS IN SUPER-RESOLUTION.

Fabian Hertel

, Gary

Mo, Sam Duwé, Peter Dedecker, Jin Zhang

4:00

pm

–6:00

pm

, B

allroom

IV

Platform

Cardiac Muscle Regulation

Co-Chairs

Maegen Ackermann, University of Maryland, Baltimore

Michael Previs, University of Vermont

1812-P

lat

4:00

pm

OVEREXPRESSION OF FOXO IN THE HEART AMELIORATES

PERFORMANCE DECLINE THROUGH ENHANCED UPS

PROCESSING IN AGING DROSOPHILA.

Anna C. Blice-Baum

,

Gaurav Kaushik, Meera C. Viswanathan, Alexander C. Zambon, Adam J.

Engler, Rolf Bodmer, Anthony Cammarato

1813-P

lat

4:15

pm

OBSCURINS’ MECHANISTIC INVOLVEMENT IN SIGNAL

TRANSDUCTION AT THE CARDIAC INTERCALATED

DISC.

Maegen Ackermann

, Nicole Perry, Aikaterini Kontrogianni-

Konstantopoulos

1814-P

lat

4:30

pm

THE N-TERMINAL HYPERVARIABLE REGION OF TROPONIN

T DIFFERENTIALLY MODULATES THE AFFINITY OF

TROPOMYOSIN-BINDING SITES.

Chinthaka K. Amarasinghe

,

Jian-Ping Jin

1815-P

lat

4:45

pm

CONSTITUTIVE PHOSPHORYLATION OF MYOSIN

REGULATORY LIGHT CHAIN (RLC) IN VIVO IS MAINTAINED

BY LOW KINASE AND PHOSPHATASE ACTIVITIES.

Audrey N. Chang

, Patrick M. Cowley, Anthony J. Baker, Kristine E.

Kamm, James T. Stull

1816-P

lat

5:00

pm

EPIGALLOCATECHIN-3-GALLATE REVERSES THE DEFECTS

IN MODULATION OF CA

2+

-SENSITIVITY BY TROPONIN I

PHOSPHORYLATION CAUSED BY HYPERTROPHIC AND

DILATED CARDIOMYOPATHY MUTATIONS IN CARDIAC

MUSCLE.

Maria Papadaki

, Petr Vikhorev, Steven Marston,

Andrew Messer