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107
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
T
U
E
S
D
A
Y
8:15
am
–10:15
am
, B
allroom
IV
Platform
Skeletal Muscle Mechanics, Structure, and
Regulation
Co-Chairs
Brett Colson, University of Minnesota
Barbara Joureau, VU University Medical Center, The Netherlands
1700-P
lat
8:15
am
ACTIVATION AND RELAXATION KINETICS IN SKELETAL AND
CARDIAC MUSCLES.
Srboljub M. Mijailovich
, Boban Stojanovic,
Djordje Nedic, Michael A. Geeves
1701-P
lat
8:30
am
ALTERNATIVE VERSIONS OF THE MYOSIN CONVERTER
VARY CROSS-BRIDGE STIFFNESS AND MUSCLE FORCE
GENERATION.
Douglas M. Swank
, Bernadette M. Glasheen,
Seemanti Ramanath, Qian Wang
1702-P
lat
8:45
am
INTERMOLECULAR COOPERATIVITY OF SKELETAL MYOSINS
ENHANCES FORCE OUTPUT IN MYOFILAMENTS.
Motoshi Kaya
, Yoshiaki Tani, Takumi Washio, Toshiaki Hisada, Hideo
Higuchi
1703-P
lat
9:00
am
SHORTENING-INDUCED FORCE DEPRESSION IN SINGLE
SARCOMERES IS ABOLISHED BY MGADP-ACTIVATION.
Neal Trecarten
, Fabio C. Minozzo, Felipe S. Leite, Dilson E. Rassier
1704-P
lat
9:15
am
FORCE-SARCOMERE LENGTH RELATIONS IN PATIENTS WITH
THIN FILAMENT MYOPATHY CAUSED BY MUTATIONS IN
NEB, ACTA1, TPM2, TPM3, KBTBD13, KLHL40 AND KLHL41.
Barbara Joureau
, J.M de Winter, Christopher T. Pappas, Edoardo
Malfatti, Alan Beggs, Nigel Clarke, Norma Romero, Carol Gregorio,
Henk Granzier, Ger J.M. Stienen, Coen C.A Ottenheijm
1705-P
lat
9:30
am
AN ACTIVE ROLE FOR THE Z-BAND DURING CONTRACTION
AND RELAXATION. Lloyd Zhao, Lanette R. Fee, Sehyang Han,
Michael K. Reedy,
Robert J. Perz-Edwards
1706-P
lat
9:45
am
EFFECTS OF CARDIAC MYOSIN BINDING PROTEIN-C
ON ACTIN MOTILITY ARE EXPLAINED WITH A DRAG-
ACTIVATION-COMPETITION MODEL.
SamWalcott
, Steffen
Docken, Samantha P. Harris
1707-P
lat
10:00
am
THE MYOSIN SUPER-RELAXED STATE IS REGULATED BY
ESTRADIOL.
Brett A. Colson
, Karl J. Petersen, Brittany C. Collins,
David D. Thomas, Dawn A. Lowe
8:15
am
–10:15
am
, R
oom
307/308
Platform
Intracellular Channels and Calcium Sparks
and Waves
Co-Chairs
Montserrat Samso, Carnegie Mellon University
Qiu-Xing Jiang, University of Texas Southwestern Medical Center
1708-P
lat
8:15
am
STRUCTURAL INSIGHTS INTO THE NATURE OF THE UNIQUE
ANION BINDING SITE WITHIN THE CARDIAC RYANODINE
RECEPTOR N-TERMINAL REGION AND ASSOCIATED DISEASE
MUTATIONS.
Siobhan Wong
, Michele Bedin, Filip Van Petegem
1709-P
lat
8:30
am
CROSSTALK BETWEEN RYR2 OXIDATION AND
PHOSPHORYLATION CONTRIBUTES TO CARDIOMYOPATHY
IN MICE WITH DUCHENNE MUSCULAR DYSTROPHY.
George G. Rodney
, Qiongling Wang, Guoliang Wang, Xander H.T.
Wehrens
1710-P
lat
8:45
am
SECRETONEURIN, A NOVEL ENDOGENOUS CAMKII
INHIBITOR, AUGMENTS CARDIOMYOCYTE CALCIUM
HANDLING AND INHIBITS ARRHYTHMOGENIC CALCIUM
RELEASE. Anett H. Ottesen, Cathrine R. Carlson, Andrew G. Edwards,
Ole J. B. Landsverk, Rune F. Johansen, Morten K. Moe, Magnar Bjørås,
Mats Stridsberg, Torbjørn Omland, Geir Christensen, Helge Røsjø,
William E. Louch
1711-P
lat
9:00
am
LARGE-SCALE, AUTOMATED CALCIUM SPARK ANALYSIS
USING ISPARK REVEALS FUNCTIONAL AND SPATIAL
REMODELING DURING CARDIAC HYPERTROPHY. Qinghai
Tian, Laura Schröder, Aline Flockerzi, Andre Zeug, Lars Kaestner,
Peter Lipp
1712-P
lat
9:15
am
REGULATION OF CALCIUM CLOCK-MEDIATED PACEMAKING
BY INOSITOL-1,4,5-TRISPHOSPHATE RECEPTORS IN MOUSE
SINOATRIAL NODAL CELLS.
Nidhi Kapoor
, Andrew Tran, Jeanney
Kang, Rui Zhang, Kenneth D. Philipson, Joshua I. Goldhaber
1713-P
lat
9:30
am
STRUCTURAL STUDIES OF IP3R BY CRYOEM.
Qiu-Xing Jiang
,
Hui Zheng, Marc Llaguno
1714-P
lat
9:45
am
MULTIPLE CLOSED STATES OF THE RYANODINE RECEPTOR
DETERMINED BY CRYOEM. Pablo Castro-Hartmann, Joshua Lobo,
Montserrat Samso
1715-P
lat
10:00
am
CRYSTAL STRUCTURES OF THE RYANODINE RECEPTOR
SPRY2 DOMAIN.
Kelvin Lau
, Filip Van Petegem
8:15
am
–10:15
am
, R
oom
309/310
Platform
Membrane Structure
Co-Chairs
Stephanie Tristram-Nagle, Carnegie Mellon University
Helgi Ingolfsson, Cornell University
1716-P
lat
8:15
am
INTERACTION OF HIV-1 GAG PROTEIN’S MA MEMBRANE
BINDING DOMAIN WITH MEMBRANE MIMICS PROBED BY
LOW- AND WIDE-ANGLE X-RAY SCATTERING. Lauren O’Neil,
Leah Langer, Davina Perera, Zachary Dell, John F. Nagle,
Stephanie Tristram-Nagle
1717-P
lat
8:30
am
INFLUENCE OF DOMAIN SIZE ON STRUCTURE AND ELASTIC
FLUCTUATIONS IN COMPLEX LIPID MIXTURES.
Peter Heftberger
, Benjamin Kollmitzer, Frederick Heberle, Jonathan
Nickels, John Katsaras, Georg Pabst
1718-P
lat
8:45
am
PHASE COEXISTENCE IN LIPID MEMBRANES INDUCED BY
BUFFERING AGENTS AND CHARGED LIPID HEADGROUPS.
Merrell A. Johnson, Soenke Seifert, Millicent A. Firestone, Horia I.
Petrache,
Ann C. Kimble-Hill