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Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
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60-P
lat
8:15
am
ROLE OF DESOLVATION IN THERMODYNAMICS AND
KINETICS OF LIGAND BINDING TO A PROTEIN.
Jagannath Mondal
, Richard Friesner, Bruce J. Berne
61-P
lat
8:30
am
INSIGHTS INTO THE STABILIZING ROLE OF CHOLESTEROL
FOR THE AMYLOID PRECURSOR PROTEIN.
Martina
Audagnotto
, Matteo Dal Peraro
62-P
lat
8:45
am
PHARMACOPHORE MODELING USING SITE-
IDENTIFICATION BY LIGAND COMPETITIVE SATURATION
(SILCS) METHOD WITH MULTIPLE PROBE MOLECULES.
Wenbo Yu
, E. Prabhu Raman, Sirish Kaushik Lakkaraju, Lei Fang,
Alexander D. MacKerell Jr.
63-P
lat
9:00
am
QUANTIFYING MACROMOLECULAR CONFORMATIONAL
TRANSITION PATHWAYS.
Oliver Beckstein
, Sean L. Seyler, Avishek
Kumar, Michael F. Thorpe
64-P
lat
9:15
am
COMPUTATIONAL DESIGN OF REPEAT-PROTEINS WITH A
PREDEFINED GEOMETRY.
Sebastian Rämisch
, Ulrich Weininger,
Jonas Martnisson, Mikael Akke, Ingemar André
65-P
lat
9:30
am
COMPUTATIONAL PREDICTION OF G-QUADRUPLEX
FORMATION.
Jacob S. Calvert
, Alex Kreig, Saurabh Sinha, Sua Myong
66-P
lat
9:45
am
PROTEIN AND RNA STRUCTURE PREDICTION BY
INTEGRATION OF CO-EVOLUTIONARY INFORMATION INTO
MOLECULAR SIMULATION. Eleonora De Leonardis, Benjamin
Lutz, Simona Cocco, Remi Monasson, Hendrik Szurmant, Martin Weigt,
Alexander Schug
67-P
lat
10:00
am
STRUCTURAL ENSEMBLES OF INTRINSICALLY DISORDERED
PROTEINS USING MOLECULAR DYNAMICS SIMULATION.
Sarah Rauscher
, Vytautas Gapsys, Bert de Groot, Helmut Grubmüller
8:15
am
–10:15
am
, B
allroom
IV
Platform
Protein-Nucleic Acid Interactions I
Co-Chairs
Svea Grieb, Technical University of Dresden, Germany
Beat Fierz, École Polytechnique Fédérale de Lausanne, Switzerland
68-P
lat
8:15
am
BINDING COMPETITION STUDIED WITH SINGLE MOLECULE
FRET: THE INTEGRON RECOMBINASE OUTCOMPETES
THE SINGLE-STRANDED DNA BINDING PROTEIN FOR ITS
RECOMBINATION SITE.
M. Svea Grieb
, Varsha Natarajan, Marko
Swoboda, Michael Schlierf
69-P
lat
8:30
am
SINGLE-MOLECULE FRET FOR DYNAMIC STRUCTURAL
BIOLOGY: DNA POLYMERASE I STRUCTURE AND
MECHANISM WITH ANGSTROM PRECISION.
Marko Sustarsic
,
Timothy Craggs, Johannes Hohlbein, Andrew Cuthbert, Nicholas Taylor,
Hendrik Kaju, Majid Mosayebi, Jonathan Doye, Achillefs N. Kapanidis
70-P
lat
8:45
am
HETEROCHROMATIN ASSEMBLY AND DYNAMICS ON THE
SINGLE MOLECULE LEVEL. Sinan Kilic, Bachmann Andreas, Louise
Bryan,
Beat Fierz
71-P
lat
9:00
am
RNA UNWINDING BY THE HELICASE MTR4P AND THE
TRAMP COMPLEX INVESTIGATED VIA HIGH-RESOLUTION
OPTICAL TRAPPING.
Eric M. Patrick
, Sukanya Srinivasan, Eckhard
Jankowsky, Matthew J. Comstock
72-P
lat
9:15
am
ELECTROSTATIC INTERACTION EFFECTS ON THE BINDING
OF SPLICEOSOMAL U1A PROTEIN-SL2 RNA HAIRPIN.
Zhaleh Ghaemi
, Irisbel Guzman, Martin Gruebele, Zaida Luthey-
Schulten
73-P
lat
9:30
am
CHROMOSOME REORGANIZATION BY THE HIGHLY
COOPERATIVE DPS PROTEIN.
Natalia Vtyurina
, David Dulin,
Margreet Docter, Nynke Dekker, Anne Meyer, Elio Abbondanzieri
74-P
lat
9:45
am
ASYMMETRIC NUCLEOSOME DISASSEMBLY WITH
DISRUPTED HISTONES REVEALED BY TIME RESOLVED SMALL
ANGLE X-RAY SCATTERING WITH CONTRAST VARIATION.
Yujie Chen
, Joshua M. Tokuda, Traci Topping, Julie L. Sutton, Steve P.
Meisburger, Suzette A. Pabit, Lisa M. Gloss, Lois Pollack
75-P
lat
10:00
am
UNDERSTANDING WITHOUT READING: ANALOGUE
ENCODING OF PHYSICOCHEMICAL PROPERTIES OF
PROTEINS IN THEIR COGNATE MESSENGER RNA.
Anton A. Polyansky
, Mario Hlevnjak, Bojan Zagrovic
8:15
am
–10:15
am
, R
oom
307/308
Platform
Protein Structure and Conformation I
Co-Chairs
Silvina Matysiak, University of Maryland
Michelle Peckham, University of Leeds, United Kingdom
76-P
lat
8:15
am
ROLE OF INTERFACES IN PEPTIDE FOLDING AND
AGGREGATION.
Sai Janani Ganesan
, Silvina Matysiak
77-P
lat
8:30
am
COMBINING NEUTRON REFLECTIVITY AND HYDROGEN
DEUTERIUM EXCHANGE MASS SPECTROMETRY TO RESOLVE
STRUCTURAL DETAILS OF MEMBRANE ASSOCIATED
PROTEINS.
Michael S. Kent
, Bulent Akgun, Hirsh Nanda, Gregory F.
Pirrone, John Engen
78-P
lat
8:45
am
international
travel awardee
EFFECT OF MOLECULAR CROWDING ON THE STRUCTURE
AND DYNAMICS OF HUMAN APO AND HOLO TRANSFERRIN
USING 2D-IR CORRELATION SPECTROSCOPY.
Sherif Abbas
,
Feride Severcan, Parvez I. Haris
79-P
lat
9:00
am
STRUCTURAL INSIGHT INTO THE PHOSPHOINOSITIDE-
REGULATED CELLULAR DYNAMICS OF ALPHA-ACTININ.
Andrea Ghisleni
, Euripides De Almeida Ribeiro, Nikos Pinotsis, Mark R.
Holt, Pauline Bennett, Kristina Djinovic-Carugo, Mathias Gautel
80-P
lat
9:15
am
DETERMINING HOW MANY IONIC INTERACTIONS ARE
NEEDED FOR THE HIGH STABILITY OF SINGLE ALPHA
HELICAL (SAH) DOMAINS. Marcin D. Wolny, Matthew R. Batchelor,
Peter J. Knight, Emanuele Paci,
Michelle Peckham