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14

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

81-P

lat

9:30

am

NMR EVIDENCE FOR UNUSUAL BIFURCATED HYDROGEN

BONDING IN THE TXXH ALPHA-HELIX N-CAPPING MOTIF.

Matthew R. Preimesberger

, Ananya Majumdar, Tural Aksel, Kevin

Sforza, Doug Barrick, Juliette T.J. Lecomte

82-P

lat

9:45

am

OXIDATION INCREASES THE STRENGTH OF THE

METHIONINE-AROMATIC INTERACTION.

Andrew K. Lewis

,

Alessandro Cembran, Tiffany L. Senkow, Ryan Mahling, Gabriella T.

Perell, Megan R. McCarthy, Cheng Her, Benjamin T. Horn, Christopher

C. Valley, Christine B. Karim, Jiali Gao, William C. Pomerantz, David D.

Thomas, Anne Hinderliter, Jonathan N. Sachs

83-P

lat

10:00

am

ELECTROSTATICS INSIDE THE SECY TRANSLOCON.

Sara Capponi

, Stephen H. White

8:15

am

–10:15

am

, R

oom

309/310

Platform

Membrane Physical Chemistry I

Co-Chairs

Rumiana Dimova, Max Planck Institute of Colloids

and Interfaces, Germany

Ilya Levental, University of Texas Health Medical Center

84-P

lat

8:15

am

DIFFERENTIATION OF PLASMA MEMBRANE COMPOSITION

AND PHYSICAL PROPERTIES.

Ilya Levental

, Kandice R. Levental

85-P

lat

8:30

am

REAL-TIME IMAGING OF NANOSCOPIC LIPID DOMAINS

USING ISCAT. Gabrielle de Wit, John S. H. Danial, Philipp Kukura,

Mark I. Wallace

86-P

lat

8:45

am

A FUNDAMENTAL FORCE THAT REGULATES NANO-

CLUSTERING OF PROTEINS IN BIOLOGICAL MEMBRANES.

Kranthi Kiran Mandadapu

, Shachi Katira, Suriyanarayanan

Vaikuntanathan, Berend Smit, David Chandler

87-P

lat

9:00

am

THEORY OF REGISTERED AND ANTIREGISTERED PHASE

SEPARATION IN MIXED AMPHIPHILIC BILAYERS.

John J. Williamson

, Peter D. Olmsted

88-P

lat

9:15

am

HOW GM1 AFFECTS THE PHASE STATE AND MECHANICAL

PROPERTIES OF PHOSPHOLIPID MEMBRANES. Nico Fricke,

Rumiana Dimova

89-P

lat

9:30

am

EXAMINING THE EFFECTS OF CHOLESTEROL: LAURDAN

AND PATMAN SEE IT DIFFERENTLY.

Emma R. Moulton

, Kelsey J.

Hirsche, Monica L. Hobbs, Morgan M. Schwab, John D. Bell

90-P

lat

9:45

am

ORIENTATIONAL TEXTURE OF MEMBRANE DOMAINS:

EFFECT OF LIPID COMPOSITION AND BINDING OF A

BACTERIAL TOXIN.

Adam C. Simonsen

, Jes Dreier, Vita Solovyeva,

Jonas C. Jeppesen, Jonathan Brewer

91-P

lat

10:00

am

PLASMA MEMBRANE VESICLE CRITICAL TEMPERATURE

SCALES WITH GROWTH TEMPERATURE IN A ZEBRAFISH

CELL LINE. Margaret Burns, Jing Wu, Kathleen Wisner,

Sarah Veatch

8:15

am

–10:15

am

, R

oom

314/315

Platform

Ion Channels, Pharmacology, and Disease

Co-Chairs

David Busath, Bringham Young University

Lyanne Schlichter, University of Toronto, Canada

92-P

lat

8:15

am

MOLECULAR DYNAMICS OF AMANTADINE BLOCK IN M2 OF

INFLUENZA A: WT VS S31N. Mitchell L. Gleed, Harris Ioannidis,

Antonios Kolocouris,

David D. Busath

93-P

lat

8:30

am

POTENTIATION OF CFTR GATING BY AN ENERGETICALLY

ADDITIVE MECHANISM.

Han-I Yeh

, Jiunn- Tyng Yeh, Tzyh-Chang

Hwang

94-P

lat

8:45

am

AFFINITY CALCULATIONS FOR LIPOPHILIC MODULATORS

BINDING TO ISOLATED SITES ON GABA(A) RECEPTORS.

Sruthi Murlidaran

, Reza Salari, Grace Brannigan

95-P

lat

9:00

am

SLC6A14 MODIFIES FLUID SECRETORY CAPACITY OF CYSTIC

FIBROSIS AFFECTED EPITHELIUM BY ENHANCING CFTR

CHANNEL FUNCTION.

Saumel Ahmadi

, Catherine Luk, Sunny Xia,

Michelle Di Paola, Timothy Chung, Johanna Rommens, Christine Bear

96-P

lat

9:15

am

ENHANCED ACTIVATION OF AN AMINO-TERMINALLY

TRUNCATED ISOFORM OF VOLTAGE-GATED PROTON

CHANNEL HVCN1 ENRICHED IN MALIGNANT B CELLS.

Elayne Hondares, Mark Brown, Boris Musset, Deri Morgan, Vladimir V.

Cherny, Christina Taubert, Mandeep K. Bhamrah, David Coe, Federica

Marelli-Berg, John G. Gribben, Martin JS Dyer, Melania Capasso,

Thomas E. DeCoursey

97-P

lat

9:30

am

POSITIVE KCA CHANNEL GATING MODULATORS WITH

SELECTIVITY FOR KCA3.1.

Brandon M. Brown

, Nichole Coleman,

Vladimir Yarov-Yarovoy, Heike Wulff

98-P

lat

9:45

am

EXPRESSION AND CONTRIBUTIONS OF TRPM7 AND

KCA2.3/SK3 CHANNELS TO THE INCREASED MIGRATION

AND INVASION OF MICROGLIA IN ANTI-INFLAMMATORY

ACTIVATION STATES. Tamjeed Siddiqui, Starlee Lively, Roger

Ferreira, Raymond Wong,

Lyanne Schlichter

99-P

lat

10:00

am

ATOMIC BASIS FOR POTASSIUM CHANNEL POTENTIATION

BY A NOVEL CLASS OF ANTI-EPILEPTIC DRUGS.

Robin Y. Kim

,

Michael C. Yau, Stephan A. Pless, Jason D. Galpin, Christopher A. Ahern,

Harley T. Kurata

8:15

am

–10:15

am

, R

oom

316/317

Platform

Kinesins, Dyneins, and Other

MT-based Motors

Co-Chairs

Sarah Rice, Northwestern University

Etsuko Muto, Riken Brain Science Institute, Japan

100-P

lat

8:15

am

KINESIN-5 ACTS AS A MICROTUBULE STABILIZER,

POLYMERASE AND PLUS-TIP TRACKER. Yalei Chen,

William O.

Hancock