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15

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

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101-P

lat

8:30

am

WHY ARE KINESIN-2 KIF3AB AND KIF3AC SO PROCESSIVE?

Stephanie Guzik-Lendrum

, Katherine C. Rank, Brandon Bensel, Ivan

Rayment, Susan P. Gilbert

102-P

lat

8:45

am

SRC KINASE PHOSPHO-REGULATION OF THE HUMAN

MITOTIC KINESIN EG5.

Sarah Rice

, Kathleen M. Gifford, Joshua S.

Waitzman, Taylor Poor, Barbara Mann, Patricia Wadsworth

103-P

lat

9:00

am

EMERGENCE OF LARGE-SCALE VORTICES OF

MICROTUBULES COLLECTIVELY DRIVEN BY AXONEMAL

DYNEINS. Naoki Kanatani,

Kazuhiro Oiwa

104-P

lat

9:15

am

ULTRASTRUCTURE OF DYNACTIN COMPLEX: A MEDIATOR

OF CYTOPLASMIC DYNEIN.

Saikat Chowdhury

, Stephanie A.

Ketcham, Trina A. Schroer, Gabriel C. Lander

105-P

lat

9:30

am

A MECHANICAL SWITCH FROM DIFFUSION TO

DIRECTIONAL MOTION ACTIVATES ATPASE IN DYNEIN

MOTOR. Seiichi Uchimura, Takashi Fujii, Hiroko Takazaki, Rie

Ayukawa, Yosuke Nishikawa, Itsushi Minoura, You Hachikubo, Genji

Kurisu, Kazuo Sutoh, Takahide Kon, Keiichi Namba,

Etsuko Muto

106-P

lat

9:45

am

CYTOPLASMIC DYNEIN RING TILTING DETECTED BY

COMBINED POLTIRF AND SUB-PIXEL PARTICLE TRACKING

OF SEMICONDUCTOR QUANTUM RODS.

Lisa G. Lippert

, Tali

Dadosh, Benjamin T. Diroll, Jeffrey T. Hallock, Christopher B. Murray,

Erika LF Holzbaur, Samara L. Reck-Peterson, Yale E. Goldman

107-P

lat

10:00

am

BIDIRECTIONAL HELICAL MOTILITY OF CYTOPLASMIC

DYNEIN AROUND MICROTUBULES.

Sinan Can

, Mark DeWitt,

Ahmet Yildiz

8:30

am

–10:30

am

, R

oom

333

Minority Affairs Committee Meeting

9:00

am

–10:00

am

, R

oom

301/302/303

Career Center Workshop

Selling Yourself to the Life Sciences Industry

The industrial employer is looking for a different set of skills and

attitudes than either the academic or government employer. Learn

what the pharmaceutical/biotechnology industries want to hear from

potential employees and why. Learn how to develop and best position

your marketing message in order to improve the chances of a successful

industrial job search.

10:00

am

–5:00

pm

, H

all

C

Biomolecular Discovery Dome

Visit this 3-D portable Dome, sponsored by the Public Affairs Committee,

to see how difficult biophysical topics can be made accessible to high

school students and the public. Short videos that communicate the

excitement of looking at macromolecular complexes and understanding

the molecular basis for life are being shown throughout the week.

10:00

am

–5:00

pm

, H

all

C

Exhibits

10:15

am

–11:00

am

, H

all

C

Coffee Break

10:30

am

–11:30

am

, R

oom

301/302/303

Career Center Workshop

Career Planning and Job Searching for

Science Professionals:

Academic Opportunities

Learn how to create a flexible career plan for yourself, and identify and

leverage your skills, expertise and experience to find a career (not just

a job) that is right for you. Special emphasis will be placed on tips for

finding and launching a career in academia, but we will also incorporate

the development of a contingency plan for the unexpected twists and

turns in life.

10:30

am

–12:00

pm

, H

all

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B

Exhibitor Presentation

Carl Zeiss Microscopy

Technology Innovations from ZEISS, the New ZEISS LSM 880

Confocal with Airyscan and the ZEISS Lightsheet Z.1

New microscopes from ZEISS address both ends of the spectrum of

samples, live high speed imaging with superresolution and high speed

imaging of large live and fixed tissues. Learn how the ZEISS LSM 880

with Airyscan maintains the mantra that each photon of emission light is

precious, while expanding the triangle of sensitivity, resolution and speed

of acquisition.

The LSM 880 with Airyscan allows you to use multicolor samples with

any label and get image quality like you’ve never seen before. With

Airyscan you are always able to select the optimal acquisition strategy

for your sample: Simply decide whether you want to gain 1.7x higher

resolution in all three dimensions – resulting in a 5x smaller confocal

volume. Or push the sensitivity beyond the limits of all conventional

confocals. Or use the increase in signal-to-noise ratio to speed up your

image acquisition.

Traditionally, deeply imaging into intact tissue typically requires

multiphoton excitation to penetrate deeper than near the surface of a

tissue. Using a “clearing” method to remove the light obstructing opaque

molecules from a tissue has been another technique for deep imaging.

Techniques such as SCALE, CLARITY, ClearT, SeeDB, CUBIC and

others have allowed researchers to image deeper than a millimeter into

cleared animal model brains and organs.

The ZEISS Lightsheet Z.1 features high speed image acquisition and

greatly reduced photodamage making imaging of live developmental

samples and fixed and cleared tissues easier than ever before. Come learn

about using the innovative ZEISS Lightsheet Z.1 microscope for imaging

of fixed and cleared tissues.

Presenters

Joseph Huff, Product Marking Manager, Laser Scanning and

Superresolution Microscopy, Carl Zeiss Microscopy LLC

Scott Olenych, Product Marketing Manager, Imaging Products, Carl Zeiss

Microscopy LLC

10:30

am

–12:30

pm

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oom

313

International Relations Committee Meeting