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21

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

S

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R

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A

Y

F

R

I

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A

Y

168-Symp

5:30

pm

AN INTEGRATIVE APPROACH TO THIN FILAMENT CARDIO-

MYOPATHIES: FROM MOLECULAR AND COMPUTATIONAL

BIOPHYSICS TO MICE.

Jil Tardiff

4:00

pm

–6:00

pm

, B

allroom

IV

Platform

Optical Microscopy and Super-Resolution

Imaging I

Co-Chairs

Keith Lidke, University of New Mexico

Christopher Kelly, Wayne State University

169-Plat

4:00

pm

REFLECTED BEAM LIGHT-SHEET MICROSCOPY FOR WHOLE-

CELL 3D SUPER-RESOLUTION IMAGING.

Marjolein BM

Meddens

, Sheng Liu, Conrad D. James, Keith A. Lidke

170-P

lat

4:15

pm

PROBING THE TRANSCRIPTION CYCLE IN REAL-TIME WITH

3D SUPERRESOLUTION INTERFEROMETRY.

Guanshi Wang

,

Jesse Hauver, Zachary Thomas, Seth A. Darst, Alexandros Pertsinidis

171-P

lat

4:30

pm

minority affairs

travel awardee

RESOLVING NANOSCALE CURVATURE ON LIPID BILAYERS

WITH POLARIZED LOCALIZATION MICROSCOPY.

Abir

Maarouf

, Rebecca Lynn Meerschaert, Christopher V. Kelly

172-P

lat

4:45

pm

SPATIAL AND FUNCTIONAL ORGANIZATION OF BACTERIAL

SUBCELLULAR STRUCTURES IN SUPERRESOLUTION.

Jie Xiao

,

Carla Coltharp, Xiaoli Weng, Jackson Buss, Xinxing Yang, Arvin Lagda

173-P

lat

5:00

pm

DISEASE PHENOTYPING WITH SUB-RESOLUTION PRECISION

BY SINGLE MOLECULE TRACKING IN LIVE ANIMALS. Hong

Zhan, Ramunas Stanciauskas, Christian Stigloher, Kevin Dizon, Maelle

Jospin, Jean-Louis Bessereau,

Fabien Pinaud

174-P

lat

5:15

pm

SUPER RESOLUTION FLUORESCENCE MICROSCOPY BY

CATHODOLUMINESCENCE-ACTIVATED EXCITATION.

Connor

G. Bischak

, Craig L. Hetherington, Jake T. Precht, Claire E. Stachelrodt,

Zhe Wang, Darrell G. Schlom, Naomi S. Ginsberg

175-P

lat

5:30

pm

3D SUPERRESOLUTION MICROSCOPY BY SUPERCRITICAL

ANGLE DETECTION.

Joran Deschamps

, Markus Mund, Jonas Ries

176-P

lat

5:45

pm

SUPER RESOLUTION IMAGING AND TRACKING OF PROTEIN-

PROTEIN INTERACTIONS IN SUB DIFFRACTION CELLULAR

SPACE.

Zhen Liu

, Dong Xing, Qian Peter Su, Yun Zhu, Jiamei Zhang,

Xinyu Kong, Boxin Xue, Sheng Wang, Hao Sun, Yile Tao, Yujie Sun

4:00

pm

–6:00

pm

, R

oom

307/308

Platform

TRP Channels

Co-Chairs

Elenora Zakharian, University of Illinois College of Medicine

Jie Zheng, University of California, Davis

177-Plat

4:00

pm

SURFACE CHARACTERIZATION AND MEMBRANE INTERAC-

TION OF DOUBLE-KNOT TOXIN, AN ACTIVATOR OF TRPV1

CHANNELS.

Chanhyung Bae

, Andres Jara-Oseguera, Dmitriy V.

Krepkiy, Jaeha Ryu, Jae Il Kim, Kenton J. Swartz

178-P

lat

4:15

pm

HIGH TEMPERATURE SENSITIVITY IS INTRINSIC TO

VOLTAGE-GATED POTASSIUM CHANNELS.

Fan Yang

, Jie Zheng

179-P

lat

4:30

pm

PERMEATION AND DYNAMICS OF AN OPEN-ACTIVATED

TRPV1 CHANNEL.

Carmen Domene

, Leonardo Darre, Simone Furini

180-P

lat

4:45

pm

THE L596-W733 BOND BETWEEN S4-S5 LINKER AND TRP

DOMAIN MAINTAINS BASAL ACTIVITY AND ENABLES

INACTIVATION OF TRPV4.

Jinfeng Teng

, Stephen Loukin, Andriy

Anishkin, Ching Kung

181-P

lat

5:00

pm

COMPARATIVE SEQUENCE ANALYSIS SUGGESTS A UNIFIED

GATING MECHANISM FOR TRP CHANNELS.

Vincenzo Carnevale

, Eugene Palovcak, Lucie Delemotte, Michael Klein

182-P

lat

5:15

pm

EFFECTS OF INACTIVATION OF TRPM7 KINASE ACTIVITY ON

ITS CHANNEL ACTIVITY IN MICE. Taku Kaitsuka, Chiaki Katagiri,

Pavani Beesetty, Kenji Nakamura, Siham Hourani, Kazuhito Tomizawa,

J. Ashot Kozak

, Masayuki Matsushita

183-P

lat

5:30

pm

TEMPERATURE AND VOLTAGE COUPLING TO TRPM8

CHANNEL OPENING. Natalia Raddatz,

Juan P. Castillo

, Carlos

Gonzalez, Osvaldo Alvarez, Ramon Latorre

184-P

lat

5:45

pm

TRPM8 IS AN IONOTROPIC TESTOSTERONE RECEPTOR.

Swapna Asuthkar, Lusine Demirkhanyan, Xiaohui Sun, Pia Elustondo,

Vivek Krishnan, Padmamalini Baskaran, Kiran Kumar Velpula, Baskaran

Thyagarajan, Evgeny Pavlov,

Eleonora Zakharian

4:00

pm

–6:00

pm

, R

oom

309/310

Platform

Protein Lipid Interactions I

Co-Chairs

Blake Mertz, West Virginia University

Svetla Stoilova-McPhie, University of Texas Medical Branch at Galveston

185-P

lat

4:00

pm

EXPERIMENTAL AND COMPUTATIONAL STUDIES OF

PULMONARY SURFACTANT PROTEIN SP-B INTERACTING

WITH LIPID BILAYERS.

Mohammad Hassan Khatami

,

Ivan Saika-Voivod, Valerie Booth

186-P

lat

4:15

pm

CREATION OF WATER-SOLUBLE INTEGRAL MEMBRANE

PROTEINS USING AN ENGINEERED AMPHIPATHIC PROTEIN

“SHIELD”.

Dario Mizrachi

187-P

lat

4:30

pm

VALIDATING THE RETINAL FLIP OF RHODOPSIN USING

MOLECULAR DYNAMICS. Jun Feng,

Blake Mertz

188-P

lat

4:45

pm

HIV GP41-ANTIBODY INTERACTION AT THE VIRAL

MEMBRANE INTERFACE DEFINED BY EPR SPECTROSCOPY.

Likai Song

, Zhen-Yu J. Sun, Mikyung Kim, Pavanjeet Kaur, Gerhard

Wagner, Ellis L. Reinherz