27
Biophysical Society 59
th
Annual Meeting, Baltimore, Maryland
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271-P
os
B
oard
B51
THERMODYNAMIC PROPERTIES OF ELP-LABELLED
DOXORUBICIN, A DRUG DELIVERY SYSTEM.
Valeria Zai-Rose
272-P
os
B
oard
B52
UNDERSTANDING THE FUNCTION OF A PRO-ANGIOGENIC
POLYPEPTIDE HFGF-1 WITH A CANCER INHIBITOR
IMATINIB.
Tulsi Modi
, Oluwadamilola Filani, Jason Payne, Raja
Murthy
273-P
os
B
oard
B53
A SHARED BINDING SITE FOR PROPOFOL AND THIOPENTAL
IN ELIC.
Monica N. Kinde
, Weiming Bu, Edom Seyoum, Qiang Chen,
Marta M. Wells, David D. Mowrey, Roderic G. Eckenhoff, Yan Xu, Pei
Tang
274-P
os
B
oard
B54
CRYSTAL VIEW OF ANESTHETICS AND ALCOHOLS BOUND IN
THE PORE OF ELIC.
Qiang Chen
, Monica N. Kinde, Aina E. Cohen,
Pei Tang, Yan Xu
275-P
os
B
oard
B55
ANALYSIS OF ANTIFOLATE DRUGS WITH DISEASE TISSUE
SPECIFICITY.
Siobhan M. Deis
, Charles E. Dann III
276-P
os
B
oard
B56
PKA-DEPENDENT POTENTIATION MECHANISMS OF HUMAN
CFTR ACTIVITY.
Guangyu Wang
277-P
os
B
oard
B57
KINASE STRUCTURAL DYNAMICS ENABLES TIGHT AND
SELECTIVE BINDING OF INHIBITORS.
Roman V. Agafonov
, Chris
Wilson, Vanessa Buosi, Renee Otten, Dorothee Kern
278-P
os
B
oard
B58
education
travel awardee
cpow mid
-
career
travel awardee
GLUTATHIONE REDUCTASE OF
PLASMODIUM FALCIPARUM
AS AN ANTIMALARIAL DRUG TARGET OF METHYLENE
BLUE.
Socheata Lim
, Judith H. Prieto
279-P
os
B
oard
B59
EFFECTS OF MOLECULAR CROWDING ON THE BINDING
AFFINITY OF DIHYDROFOLATE FOR DIHYDROFOLATE
REDUCTASE.
Michael R. Duff
, Elizabeth E. Howell
280-P
os
B
oard
B60
QUANTIFYING THE INFLUENCE OF THE CROWDED
CYTOPLASM ON SMALL BIOMOLECULE DIFFUSION VIA
HOMOGENIZATION THEORY.
Peter M. Kekenes-Huskey
, Caitlin
E. Scott
281-P
os
B
oard
B61
SPECIFIC OR GENERAL - IT IS ALL ABOUT SOLUTE
INTERACTIONS WITH THE PORE.
Ekaterina M. Nestorovich
,
Sergey M. Bezrukov
282-P
os
B
oard
B62
USING SEDIMENTATION VELOCITY TO INVESTIGATE THE
NUCLEOTIDE-LINKED ASSEMBLY OF E. COLI CLPA.
Ryan P. Stafford
, Aaron L. Lucius
283-P
os
B
oard
B63
MACROMOLECULAR CROWDER AND LIGAND COMPETE
FOR THE CLOSED DOMAIN CLEFT OF MALTOSE BINDING
PROTEIN.
Archishman Ghosh
, Huan-Xiang Zhou
284-P
os
B
oard
B64
CHARACTERIZATION OF THE CALCIUM-BINDING AND
PEPTIDE-BINDING PROPERTIES OF ARRHYTHMOGENIC
CALMODULIN MUTANTS.
Shane D. Walton
, Norma M. Elizaga,
Hsiang-Ting Ho, Jalal K. Siddiqui, Andrew J. O’Neil, Bin Liu, Sandor
Gyorke, Jonathan P. Davis
285-P
os
B
oard
B65
LIPOYLATION MECHANISM OF P. FALCIPARUM
MITOCHONDRIAL PROTEINS.
Alfredo J. Guerra
, Gustavo A.
Afandor, Russell P. Swift, Sean T. Prigge
286-P
os
B
oard
B66
UNDERSTANDING THE MOLECULAR DETERMINANTS OF
CAPSAICIN MODE OF ACTION.
Khaled M. Elokely
, Eugene
Palovack, Lucie Delemotte, Vincenzo Carnevale, Michael L. Klein
Protein Dynamics and Allostery I
(Boards B67-B88)
287-P
os
B
oard
B67
FORMATION AND DEGRADATION OF INTERMEDIATE
HEMOGLOBIN POLYMERS ARE RESPONSIBLE FOR THE
COOPERATIVITY OF OXYGEN BINDING ISOTHERMS.
Enrico Bucci
, Stefania Pucciarelli, Mauro Angeletti
288-P
os
B
oard
B68
ROLE OF IONIC STRENGTH AND THE BOHR EFFECT IN
MODULATING THERMODYNAMIC PROFILES ASSOCIATED
WITH CO ESCAPE IN RICE NON-SYMBIOTIC HEMOGLOBIN
1.
David Butcher
, Jaroslava Miksovska
289-P
os
B
oard
B69
THE “CAGED” STATE, THE TRANSITION STATE
OF THE REGULATION OF OXYGEN-AFFINITY IN
HEMOGLOBIN.
Takashi Yonetani
, Kenji Kanaori
290-P
os
B
oard
B70
UNDERSTANDING THERMODYNAMICS OF
CONFORMATIONAL CHANGE IN THE F-ATPASE.
Nicholas Leioatts
, Helmut Grubmüller
291-P
os
B
oard
B71
KINETIC CONTROL OF O2 REACTIVITY IN H-NOX
DOMAINS.
Abdelkrim Benabbas
, Yuhan Sun, Weiqiao Zeng, Sandhya
Muralidharan, Elizabeth Boon, Paul Champion
292-P
os
B
oard
B72
PROBING FLEETING INTERACTIONS IN LARGE AND
DYNAMIC NONRIBOSOMAL PEPTIDE SYNTHETASES WITH
NOVEL NMR METHODS.
Dominique P. Frueh
, Andrew C.
Goodrich, Bradley J. Harden, Scott R. Nichols, Subrata H. Mishra
293-P
os
B
oard
B73
education
travel awardee
VISUALIZING THE INTER-DOMAIN MOTIONS OF A
PATHOGENIC PROTEIN USING SPARSE RDC DATA.
Yang Qi
,
Jeffrey W. Martin, Anthony Yan, Francois Thelot, Bruce R. Donald,
Terrence G. Oas
294-P
os
B
oard
B74
MAPPING THE CONFORMATIONAL DYNAMICS OF THE
SCAFFOLD PROTEIN PSD-95.
Claus A.M. Seidel
, Jakub Kubiak,
Suren Felekyan, Daniel Rohrbeck, James J. McCann, Mark E. Bowen