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29

Biophysical Society 59

th

Annual Meeting, Baltimore, Maryland

S

A

T

U

R

D

A

Y

F

R

I

D

A

Y

U

N

D

A

Y

319-P

os

B

oard

B99

STUDYING

α

-SYNUCLEIN MISFOLDING THROUGH FÖRSTER

RESONANCE ENERGY TRANSFER.

Conor M. Haney

, Rebecca F.

Wissner, E. James Petersson

320-P

os

B

oard

B100

INVESTIGATING THE TRIMETHYLAMINE N-OXIDE (TMAO)

INDUCED STRUCTURE OF

α

-SYNUCLEIN.

John J. Ferrie

, Rebecca

F. Wissner, E James Petersson

321-P

os

B

oard

B101

FROM MONOMERS, DIMERS TO OLIGOMERS: HOW METAL

IONS REGULATE AMYLOID BETA PORTEINS IN AMYLOID

FORMATION?

Liang Xu

, Buyong Ma

322-P

os

B

oard

B102

TRANSIENT BINDING OF ZN(II )REDIRECTS AMYLOID BETA

PEPTIDE FROM FIBRIL FORMATION.

Astrid Graslund

, Axel

Abelein, Jens Danielsson

323-P

os

B

oard

B103

SITE-SPECIFIC DYNAMICS OF A

β

1-23

AMYLOID FORMATION

AND FIBRILLAR CONFIGURATION USING AN UNNATURAL

AMINO ACID.

Deguo Du

, Haiyang Liu, Richard Lantz, Patrick Cosme,

Andrew C. Terentis, Ewa P. Wojcikiewicz, Rolando Oyola

324-P

os

B

oard

B104

minority affairs

travel awardee

SURFACE INTERACTIONS RESTRICTS AMYLOID‑

β

PEPTIDES

MOVEMENTS RESULTING IN THEIR RAPID SELF-ASSEMBLY

INTO

β

SHEETS; A MOLECULAR DYNAMICS STUDY.

Natnael B. Doilicho

, Karl F. Freed, Esmael J. Haddadian

325-P

os

B

oard

B105

BINDING OF A

β

MONOMER TO DMPC BILAYER USING

ISOBARIC-ISOTHERMAL REPLICA EXCHANGE MOLECULAR

DYNAMICS.

Christopher Lockhart

, Dmitri K. Klimov

326-Pos

Board B106

AMYLOID-

β

OLIGOMERS: NOW FOR THE STRUCTURE IN THE

MEMBRANE. Debanjan Bhowmik, Sudipta Maiti, Kaustubh Mote,

Bappaditya Chandra, Perunthiruthy Madhu

327-P

os

B

oard

B107

SMALLER LIPOSOMES ACCELERATE THE FIBRILLATION OF

AMYLOID

β

(1-40).

Mayu S. Terakawa

328-P

os

B

oard

B108

AMYLOID FIBRIL NUCLEATION IN REVERSE MICELLES.

Gozde Eskici

, Paul Axelsen

329-P

os

B

oard

B109

MICROTUBULE NETWORKS MODULATE CELLULAR

SUSCEPTIBILITY TO A

β

-MEDIATED TOXICITY. Nicole Shamitko-

Klingensmith, Jonathan W. Boyd,

Justin Legleiter

330-P

os

B

oard

B110

RECONFIGURATION OF THE ALZHEIMER’S PEPTIDE

KINETICALLY CONTROLS AGGREGATION IN ALZHEIMER’S

DISEASE. Srabasti Acharya,

Lisa J. Lapidus

331-P

os

B

oard

B111

education

travel awardee

THE ABILITY OF POLYPHENOLS TO REDUCE A

β

-INDUCED

APOPTOSIS ASSOCIATED WITH ALZHEIMER’S DISEASE.

Kayla M. Pate

, McCall Rogers, Melissa Moss

332-P

os

B

oard

B112

SELF-PROPAGATIVE REPLICATION OF AMYLOID-

β

OLIGOMERS IN ALZHEIMER DISEASE.

Dexter N. Dean

, Amit

Kumar, Kayla M. Pate, Melissa A. Moss, Vijayaraghavan Rangachari

333-P

os

B

oard

B113

ALZHEIMER’S PROTECTIVE A2T MUTATION CHANGES THE

CONFORMATIONAL LANDSCAPE OF THE A

β

1-42 MONOMER

DIFFERENTLY THAN DOES THE A2V MUTATION.

Payel Das

334-P

os

B

oard

B114

THE EFFECT OF PEPTOIDS ON A

β

AGGREGATION AND NF-

κ

B

ACTIVATION IN ALZHEIMER’S DISEASE. Kelly Moore,

Lauren M. Wolf

, J. Phillip Turner, Melissa A. Moss, Shannon Servoss

335-P

os

B

oard

B115

EFFECTS OF CARBON NANOPARTICLES ON THE

AGGREGATION OF ALZHEIMERS BETA-AMYLOID

PEPTIDE. Yunxiang Sun, Luogang Xie, Dongdong Lin, Xinju Yang,

Guanghong Wei

DNA Replication, Recombination, and

Repair (Boards B116-B136)

336-P

os

B

oard

B116

SINGLE MOLECULE STUDIES OF RPA’S SEQUENTIAL BINDING

TO SSDNA REVEALS A HIGHLY STIFF AND STABLE STATE

INDUCED BY THE BINDING OF ZINC.

Jin Chen

, Shimin Le,

Walter J. Chazin, Jie Yan

337-P

os

B

oard

B117

STUDIES OF THE FTSK DNA TRANSLOCASE USING TWO-

COLOR TETHERED FLUOROPHORE MOTION.

Peter F J May

,

Pawel Zawadzki, Lidia K. Arciszewska, David Sherratt, Achillefs N.

Kapanidis

338-P

os

B

oard

B118

UNRAVELING THE INTERPLAY BETWEEN SINGLE-STRANDED

DNA-BINDING PROTEIN, DNA POLYMERASE AND SINGLE-

STRANDED DNA.

Jordi Cabanas Danes

, Tjalle P. Hoekstra, Iddo

Heller, Erwin J.G. Peterman, Gijs J.L. Wuite

339-P

os

B

oard

B119

MECHANISTIC INSIGHTS OF HEXAMERIC HELICASE

FUNCTION PROVIDED BY SINGLE-MOLECULE FRET.

Sean M. Carney

, Sanford Leuba, Michael Trakselis

340-P

os

B

oard

B120

EFFECTS OF DNA STRUCTURAL AND TOPOLOGICAL

CONSTRAINTS ON HMGA2 BINDING.

Xiaodan Zhao

, Peter

Dröge, Jie Yan

341-P

os

B

oard

B121

SINGLE-MOLECULE ANALYSIS OF TRANSCRIPTION-COUPLED

REPAIR.

Jun Fan

, Nigel Savery, Nicolas Joly, Terence Strick

342-P

os

B

oard

B122

INVESTIGATION OF THE TUS-TER BLOCKING EFFICACY

DURING THE CHROMOSOME REPLICATION OF LIVE

ESCHERICHIA COLI CELLS.

Sriram Tiruvadi Krishnan

, M. Charl

Moolman, Roy de Leeuw, Jacob W.J. Kerssemakers, Nynke H. Dekker

343-P

os

B

oard

B123

EXTREMOPHILE DNA PHOTOLYASES: DNA REPAIR UNDER

EXTREME CONDITIONS.

Sudipto Munshi

, Brittany N. Stroud,

Yvonne M. Gindt, Robert J. Stanley

344-P

os

B

oard

B124

STRUCTURE AND NANO-MECHANICS OF DNA DURING

THE INITIAL STAGES OF METHYL-DIRECTED MISMATCH

REPAIR.

Eric A. Josephs

, Piotr E. Marszalek