150 / 226
Source:Breman JD, Henderson DA. N Engl J Med 2002;346:1300-8.
Progression of smallpox
•
Incubation Period
•
Pre-eruptive Stage:
–
abrupt onset high
fever/constitutional
symptoms
•
Macules
•
Papules
•
Vesicles
•
Pustules
•
Scabs
•
Scars