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WHA resolutions andWHO Protocol

approval process

1999WHA resolution - postpone decision on destruction until 2002

2002WHA resolution - postpone decision on destruction

2005WHA

Increased focus on “essential” public health research

Interpreted by WHO committee to preclude fundamental research

Major review of the research to the WHA in 2011

Advisory Group of Independent Experts (AGIES) review

Variola virus

research in 2010

2011WHA

Resolution to revisit in 3 years

AGIES conduct second review of

Variola virus

research in 2013

2013WHA

Request to consider question of synthetic biology

Report to be shared 2016

Virus characterization

“Genomic sequencing and limited study of

Variola virus

surface proteins derived from

geographically dispersed specimens is an

essential foundation for important future

work. Such research could be carried out

now, and could require a delay in the

destruction of known stocks, but would not

necessitate their indefinite retention.*”

*

Assessment of Future Scientific Needs for Live

Variola Virus

; N.A.Press (1999)