392-393 / 2063
ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr
collagen
fibronectin
TGF-a,ß
, TNF-a
MCP-1, MIP-1a
PDGF, RANTES
VEGF
bFGF, PDGF
IGF-1,
IL-1ß
IL-8
, MCP-1
MIP-1a, RANTES
TNF-a,
TGF-ß
bFGF, collagenase
GM-CSF,
IL-1ß
IL-6
, PDGF
PGE2
, VEGF
ICAM-1
IL-6
MCP-1
MIP-1a
Epithelium
Fibroblasts
Endo-
thelium
Dörr and Herrmann,
In: Nieder et al. (Eds.), Springer-Verlag 2003
ROS/
RNOS
Makro-
phages
Late effect signaling