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ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr

Epithelium

early

radiation

effect

additional

trauma

Endothelium

Fibroblasts

Parenchyma

late

radiation

effect

modified from: Dörr and Hendry, Radiother. Oncol. 61, 2001, 223-231

Consequential late effects (CLE): Mechanisms