ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr
Epithelium
early
radiation
effect
additional
trauma
Endothelium
Fibroblasts
Parenchyma
late
radiation
effect
modified from: Dörr and Hendry, Radiother. Oncol. 61, 2001, 223-231
Consequential late effects (CLE): Mechanisms