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ESTRO BCR Course / Pathogenesis of NT effects – W. Dörr

frequency [%]

0

100

dose

severity

time [years]

high

dose

low dose

interm.

dose

clinically relevant

effect

Tolerance doses for late responding tissues

require information on the duration of follow up!

FU1

FU2

follow

-up

Late effects – Dose-effect relationship