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ESTRO BCR Course / NT radiosensitivity and fractionation – W. Dörr
Tissue/reaction
a/b
-value
[Gy]
-
Ref.
Epidermis
Desquamation
9.1-12.5
8.6-10.6
9-12
49.6 [42.2;58.6]
Douglas and Fowler 1976
Joiner et al. 1983
Moulder and Fischer 1976
Ruifrok et al. 1994
Oral
mucosa
Ulceration
7.9 [1.8;25.8]
10.8
7.4
16.4 [14.6;18.2]
11.6 [6.8;18.9]
11.9 [7.4;20.2]
Ang et al. 1985
Moses and Kummermehr 1986 (Reanalysis)
Scalliet et al. 1987
Stüben et al. 1991
Dörr et al. 1993
Nickstadt and Dörr, unpublished
Intestine
Crypt survival
Weight loss
6.0-8.3
6.6-10.7
8-9
13.3
9-13-
Withers et a. 1976
Thames et al. 1981
Tucker et al. 1983
Huczkowski and Trott 1984
Tucker and Denekamp 1984
Urinary bladder
Impaired function
13.9 [8.4;24.6]
11.0 [7.5;16.1]
Dörr and Schultz-Hector 1992
Dörr 1995
Testis
clon. survival
12-13
Thames and Withers 1980
a/b
-value
- early effects / experimental data
Dose fractionation: LQ formalism