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ESTRO BCR Course / NT radiosensitivity and fractionation – W. Dörr

a/b

-value

- late effects / experimental data

Tissue / reaction

a/b

-value [Gy]

Ref.

Spinal cord cervical

lumbar

1.8-2.7

1.6-1.9

1.5-2.0

2.2-3.0

3.7-4.5

4.1-4.9

3.8-4.1

2.3-2.9

van der Kogel 1979

White and Hornsey 1978

Ang et al. 1983

Thames et al. 1981

van der Kogel 1979

White and Hornsey 1978

Leith et al 1981

Amals and Yuhas

Intestine

Weight loss

Rectal stenosis

3.1-5.0

Terry and Denekamp

Trott and Kummermehr 1994

Kidney

1.7-2.0

1.7-2.0

0.5-3.8

1.0

0.9-2.8

1.4-4.3

Caldwell 1975

Hopewell and Wiernik 1977

van Rongen et al. 1988

liams and Denekamp 1984

Stewart et al. 1984

Thames et al. 1988

Urinary bladder

Impaired function

6.6 [2.2;14.5]

5.8 [3.6;8.8]

4.4 [2.0;8.4]

Stewart et al. 1984

Bentzen et al. 1992

Dörr and Bentzen 1999

Lung

LD50

Breathing frequency

4.4-6.3

2.8-4.8

2.0-2.4

1.9-3.1

Wara et al. 1973

Field et al 1976

Travis et al. 1983

Parkins and Fowler 1985

Dose fractionation: LQ formalism