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ESTRO BCR Course / NT radiosensitivity and fractionation – W. Dörr

Time between fractions [min]

ED50 for fractionated irradiation [Gy]

10

12

14

16

18

20

22

a

/

b

=11.6 Gy

T

1/2

=46 min

mouse

tongue

mucosa,

early

response

0 60 120 180 240 300 360 420 480 540

8

Dörr et al., RTO 27, 1993, 36-45

Dose fractionation: Time interval