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CCA TREATED PRE-TRANSPLANT
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Retrospective, 12 patients
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Unresectable perihilar CCA ≤3cm with negative lymph nodes
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Pre-transplant:
- SBRT 3-5 fractions of 10-20Gy (Total: 50-60Gy)
- Capecitabine: 1330mg/m2/day until transplant
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6 patients transplanted, 5 partial response, 1 no responder
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1y OS after transplant 83%
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No vascular, biliary or hepatic insufficiency
Welling Th. Neoadjuvant SBRT, capecitabine, and liver transplantation for unresectable hilar
cholangiocarcinoma. Liver Transpl 2014