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HEPATIC TOXICITY SBRT STUDIES
•
Reported CTC grade ≥ 3 hepatic:
- Elevation liver enzymes
- Hyperbilirubinemia/Hypoalbuminemia/Elevation INR
- Child Pugh decline
- Death due to decompensation
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Hepatic toxicity influences prognosis:
- Greater risk of death
(Lasley FD. PRO 2015)
- 2 year survival
(Sanuki N. Hepat Research 2015)